M W Van Dyke
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Explore the profile of M W Van Dyke including associated specialties, affiliations and a list of published articles.
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Articles
41
Citations
781
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Recent Articles
1.
Shen J, Wang J, Van Dyke M
Bioorg Med Chem
. 2001 Sep;
9(9):2285-93.
PMID: 11553467
An important question in the study of ligand-DNA interactions is the determination of binding specificity. Here, we used the combinatorial method restriction endonuclease protection, selection, and amplification (REPSA) to identify...
2.
Ciotti P, Van Dyke M, Bianchi-Scarra G, Musso M
Eur J Biochem
. 2001 Feb;
268(2):225-34.
PMID: 11168355
In an attempt to identify genes encoding triple-helical DNA-binding proteins, we performed South-Western screening of a human keratinocyte cDNA expression library using a purine (Pu)-rich triplex DNA probe. We isolated...
3.
Musso M, Bianchi-Scarra G, Van Dyke M
Nucleic Acids Res
. 2000 Nov;
28(21):4090-6.
PMID: 11058104
The formation of triple-helical DNA has been implicated in several cellular processes, including transcription, replication and recombination. While there is no direct evidence for triplexes in vivo, cellular proteins that...
4.
Nelson L, Musso M, Van Dyke M
J Biol Chem
. 2000 Feb;
275(8):5573-81.
PMID: 10681538
The formation of triple helical DNA has been evoked in several cellular processes including transcription, replication, and recombination. Using conventional and affinity chromatography, we purified from Saccharomyces cerevisiae whole-cell extract...
5.
Antony T, Musso M, Hosseini M, Brand G, Greenfield N, Thomas T, et al.
Antisense Nucleic Acid Drug Dev
. 1999 Apr;
9(1):13-23.
PMID: 10192285
Linear polyamines are excellent promoters of triplex DNA formation. The effects of structural rigidization of polyamines on triplex DNA stability are not known at present. We wished to develop a...
6.
Cheng A, Wang J, Van Dyke M
Antisense Nucleic Acid Drug Dev
. 1998 Jul;
8(3):215-25.
PMID: 9669659
Efficient purine-motif triple-helix formation with guanosine/thymidine-rich oligodeoxyribonucleotides requires the presence of divalent cations (e.g., Mg2+) or polyamines at physiologic concentrations. However, under such conditions, we found that G-rich oligonucleotides were...
7.
Wang J, Sawadogo M, Van Dyke M
Biochim Biophys Acta
. 1998 Jun;
1397(2):141-5.
PMID: 9565670
Described are a series of plasmids containing combinations of adenovirus-2 major late promoter elements, including consensus TATA box and initiator, upstream of G-free transcription cassettes of various lengths. These provide...
8.
Szentirmay M, Musso M, Van Dyke M, Sawadogo M
Nucleic Acids Res
. 1998 May;
26(11):2754-60.
PMID: 9592165
An important control point for gene regulation is the frequency of initiations leading to different numbers of RNA polymerases simultaneously transcribing the same gene. To date, the only direct assay...
9.
Musso M, Nelson L, Van Dyke M
Biochemistry
. 1998 Apr;
37(9):3086-95.
PMID: 9485462
One piece of evidence indicating that triple-helical DNAs exist in vivo would be the demonstration of cellular proteins that recognize such structures. Using oligonucleotide probes containing a GT-rich purine-motif triplex,...
10.
Hardenbol P, Wang J, Van Dyke M
Bioconjug Chem
. 1997 Nov;
8(5):617-20.
PMID: 9327123
The combinatorial method restriction endonuclease protection, selection, and amplification (REPSA) was used to determine the preferred duplex DNA binding sites of the peptide N-methylpyrrolecarboxamide antibiotic distamycin A. After 12 rounds...