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M van de Wetering

Explore the profile of M van de Wetering including associated specialties, affiliations and a list of published articles. Areas
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Articles 34
Citations 3207
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Recent Articles
21.
Castrop J, van Wichen D, van de Wetering M, de Weger R, van Dongen J, Clevers H
Blood . 1995 Oct; 86(8):3050-9. PMID: 7579399
The TCF-1 gene encodes a putative transcription factor with affinity for a sequence motif occurring in a number of T-cell enhancers. TCF-1 mRNA was originally found to be expressed in...
22.
Verbeek S, Izon D, Hofhuis F, Te Riele H, van de Wetering M, Oosterwegel M, et al.
Nature . 1995 Mar; 374(6517):70-4. PMID: 7870176
Two candidate genes for controlling thymocyte differentiation, T-cell factor-1 (Tcf-1) and lymphoid enhancer-binding factor (Lef-1), encode closely related DNA-binding HMG-box proteins. Their expression pattern is complex and largely overlapping during...
23.
Dooijes D, van de Wetering M, Knippels L, Clevers H
J Biol Chem . 1993 Nov; 268(33):24813-7. PMID: 8227043
The Schizosaccharomyces pombe gene mat-Mc plays a determinative role in the sexual differentiation of the fission yeast. The mat-Mc protein has been suggested to belong to a novel family of...
24.
van de Wetering M, Oosterwegel M, van Norren K, Clevers H
EMBO J . 1993 Oct; 12(10):3847-54. PMID: 8404853
Previous studies in lymphocytes have described two DNA-binding HMG box proteins, TCF-1 and LEF-1, with affinity for the A/TA/TCAAAG motif found in several T cell-specific enhancers. Evaluation of cotransfection experiments...
25.
Oosterwegel M, van de Wetering M, Clevers H
Thymus . 1993 Sep; 22(2):67-81. PMID: 8209398
The central theme of this review is the molecular basis for commitment of cells to the T-cell lineage. Principles of transcriptional regulation are illustrated by two examples; the role of...
26.
van Houte L, Van Oers A, van de Wetering M, Dooijes D, Kaptein R, Clevers H
J Biol Chem . 1993 Aug; 268(24):18083-7. PMID: 8349685
The High Mobility Group (HMG) 1 box is a protein motif that mediates DNA binding in a novel family of transcription-regulating proteins. Several members of this family, including the lymphoid-specific...
27.
Oosterwegel M, van de Wetering M, Timmerman J, Kruisbeek A, Destree O, Meijlink F, et al.
Development . 1993 Jun; 118(2):439-48. PMID: 8223271
The recent identification of a number of T lymphocyte-specific enhancers has allowed the cloning of several novel transcription factors. Two of these, TCF-1 and LEF-1, contain a virtually identical DNA-binding...
28.
Schilham M, van Eijk M, van de Wetering M, Clevers H
Nucleic Acids Res . 1993 Apr; 21(8):2009. PMID: 8493110
No abstract available.
29.
van de Wetering M, Clevers H
Nucleic Acids Res . 1993 Apr; 21(7):1669. PMID: 8479922
No abstract available.
30.
van de Wetering M, Clevers H
EMBO J . 1992 Aug; 11(8):3039-44. PMID: 1639073
The high mobility group I (HMG) box is proposed to mediate DNA binding in a novel group of transcription-regulating proteins. Two of these, the proteins encoded by the T cell-specific...