M van Bilsen
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Explore the profile of M van Bilsen including associated specialties, affiliations and a list of published articles.
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62
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1157
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Recent Articles
11.
Gorselink M, Drost M, de Brouwer K, Schaart G, van Kranenburg G, Roemen T, et al.
Am J Physiol Endocrinol Metab
. 2002 Jan;
282(2):E348-54.
PMID: 11788366
GLUT-4 plays a predominant role in glucose uptake during muscle contraction. In the present study, we have investigated in mice whether disruption of the GLUT-4 gene affects isometric and shortening...
12.
Fasting-induced changes in the expression of genes controlling substrate metabolism in the rat heart
Van der Lee K, Willemsen P, Samec S, Seydoux J, Dulloo A, Pelsers M, et al.
J Lipid Res
. 2001 Nov;
42(11):1752-8.
PMID: 11714844
During fasting, when overall metabolism changes, the contribution of glucose and fatty acids (FA) to cardiac energy production alters as well. Here, we examined if the heart is able to...
13.
de Windt L, Willems J, Roemen T, Coumans W, Reneman R, Van der Vusse G, et al.
Am J Physiol Heart Circ Physiol
. 2001 May;
280(6):H2572-80.
PMID: 11356612
For the murine heart the relationships between ischemia-reperfusion-induced loss of cardiac function, enzyme release, high-energy phosphate (HEP), and membrane phospholipid metabolism are ill-defined. Accordingly, isolated ejecting murine hearts were subjected...
14.
Doevendans P, Bronsaer R, Lozano P, Kubalak S, van Bilsen M
Cytogenet Cell Genet
. 2000 Dec;
90(3-4):248-52.
PMID: 11124527
Recently the near complete cDNA of the regulatory atrial myosin light chain (MLC-2a) was cloned. The atrial specific isoform has been shown to be a useful molecular marker for cardiac...
15.
Van der Vusse G, van Bilsen M, Glatz J
Cardiovasc Res
. 2000 Mar;
45(2):279-93.
PMID: 10728348
Fatty acids are important energy donors for the healthy heart. These substrates are supplied to the myocardium bound to albumin to overcome their low solubility in aqueous solutions such as...
16.
Van der Lee K, Willemsen P, Van der Vusse G, van Bilsen M
FASEB J
. 2000 Mar;
14(3):495-502.
PMID: 10698964
Fatty acids are thought to play a role in the activity of uncoupling proteins (UCP) and have been shown to regulate the expression of genes encoding proteins involved in fatty...
17.
Van der Lee K, Vork M, De Vries J, Willemsen P, Glatz J, Reneman R, et al.
J Lipid Res
. 2000 Jan;
41(1):41-7.
PMID: 10627500
Long-chain fatty acids are the most important substrates for the heart. In addition, they have been shown to affect signalling pathways and gene expression. To explore the effects of long-chain...
18.
Engels W, van Bilsen M, Wolffenbuttel B, Van der Vusse G, Glatz J
Mol Cell Biochem
. 1999 May;
192(1-2):53-61.
PMID: 10331658
Diabetes mellitus generally results in an increased systemic fatty acid mobilization which can be associated with an increase in mitochondrial and peroxisomal beta-oxidation of fatty acids in selected tissues. The...
19.
de Windt L, Willems J, Reneman R, Van der Vusse G, Arts T, van Bilsen M
Pflugers Arch
. 1999 Feb;
437(2):182-90.
PMID: 9929557
An improved, isolated, left ventricular-ejecting, murine heart model is described and evaluated. Special attention was paid to the design and impedance characteristics of the artificial aortic outflow tract and perfusate...
20.
van Bilsen M, Van der Vusse G, Reneman R
Pflugers Arch
. 1998 Nov;
437(1):2-14.
PMID: 9817779
Under normal conditions the oxidation of fatty acids and glucose covers, respectively, approximately 65% and 30% of the energy demand of the beating heart. Evidence is accumulating that various pathophysiological...