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M Satish Kumar

Explore the profile of M Satish Kumar including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 230
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Recent Articles
1.
Tummala A, Ramesh V, Balakrishna N, Koyyada R, Singh A, Patnam S, et al.
Biomed Res Int . 2023 Mar; 2022:5644956. PMID: 36950250
Objective: We intend to identify differences in the clinicodemographic and laboratory findings of COVID-19 patients to predict disease severity and outcome on admission. Methods: This single-centred retrospective study retrieved laboratory...
2.
Kearns B, Pandor A, Stevenson M, Hamilton J, Chambers D, Clowes M, et al.
Pharmacoeconomics . 2016 Oct; 35(4):415-424. PMID: 27770303
As part of its single technology appraisal (STA) process, the National Institute for Health and Care Excellence (NICE) invited the company that manufactures cabazitaxel (Jevtana, Sanofi, UK) to submit evidence...
3.
Satish Kumar M, Koteiche H, Claxton D, Mchaourab H
FEBS Lett . 2008 Dec; 583(1):175-9. PMID: 19071118
A number of alphaA-crystallin mutants are associated with hereditary cataract including cysteine substitution at arginine 49. We report the formation of affinity-driven disulfide bonds in the interaction of alphaA-R49C with...
4.
Anil Kumar P, Satish Kumar M, Reddy G
Biochem J . 2007 Aug; 408(2):251-8. PMID: 17696877
The chaperone-like activity of alpha-crystallin is considered to play an important role in the maintenance of the transparency of the eye lens. However, in the case of aging and in...
5.
Mchaourab H, Satish Kumar M, Koteiche H
FEBS Lett . 2007 Apr; 581(10):1939-43. PMID: 17449033
To elucidate the structural and energetic basis of attractive protein interactions in the aging lens, we investigated the binding of destabilized mutants of betaB1-crystallin to the lens chaperones, alpha-crystallins. We...
6.
Koteiche H, Satish Kumar M, Mchaourab H
FEBS Lett . 2007 Apr; 581(10):1933-8. PMID: 17448466
A central step in understanding lens aging is to characterize the thermodynamic stability of its proteins and determine the consequences of changes in the primary sequence on their folding equilibria....
7.
Reddy G, Anil Kumar P, Satish Kumar M
IUBMB Life . 2006 Nov; 58(11):632-41. PMID: 17085382
alpha-Crystallin, a prominent member of small heat shock protein (sHsp) family and a major structural protein of the eye lens is a large polydisperse oligomer of two isoforms, alphaA- and...
8.
Satish Kumar M, Reddy P, Sreedhar B, Reddy G
Biochem J . 2005 Jun; 391(Pt 2):335-41. PMID: 15952936
Alphab-crystallin, a small heat-shock protein has been shown to prevent the aggregation of other proteins under various stress conditions. We have investigated the role of alphaB-crystallin in the reactivation of...
9.
Satish Kumar M, Kapoor M, Sinha S, Reddy G
J Biol Chem . 2005 Apr; 280(23):21726-30. PMID: 15817465
Alpha-crystallin, composed of two subunits, alphaA and alphaB, has been shown to function as a molecular chaperone that prevents aggregation of other proteins under stress conditions. The exposed hydrophobic surfaces...
10.
Satish Kumar M, Mrudula T, Mitra N, Reddy G
Exp Eye Res . 2004 Sep; 79(4):577-83. PMID: 15381041
Methylglyoxal (MGO), a potent glycating agent, forms advanced glycation end products (AGEs) with proteins. Several diabetic complications including cataract are thought to be the result of accumulation of these protein-AGEs....