M S Turker
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Explore the profile of M S Turker including associated specialties, affiliations and a list of published articles.
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50
Citations
403
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Recent Articles
1.
Kisby G, Olivas A, Park T, Churchwell M, Doerge D, Samson L, et al.
DNA Repair (Amst)
. 2009 Jan;
8(3):400-12.
PMID: 19162564
Neurons of the developing brain are especially vulnerable to environmental agents that damage DNA (i.e., genotoxicants), but the mechanism is poorly understood. The focus of the present study is to...
2.
Kisby G, Lesselroth H, Olivas A, Samson L, Gold B, Tanaka K, et al.
DNA Repair (Amst)
. 2004 May;
3(6):617-27.
PMID: 15135729
Base-excision (BER) and nucleotide-excision (NER) repair play pivotal roles in protecting the genomes of dividing cells from damage by endogenous and exogenous agents (i.e. environmental genotoxins). However, their role in...
3.
Gage B, Alroy D, Shin C, Ponomareva O, Dhar S, Sharma G, et al.
Oncogene
. 2001 Jul;
20(32):4291-7.
PMID: 11466609
The study of Ataxia-telangiectasia (A-T) has benefited significantly from mouse models with knockout mutations for the Atm (A-T mutation) locus. While these models have proven useful for in vivo studies,...
4.
Turker M
Mech Ageing Dev
. 2000 Aug;
117(1-3):1-19.
PMID: 10958919
Cancers increase during aging in mammals, and an accumulating body of evidence suggests that mutational events too do likewise. Mutational events are intimately involved in the malignant process. One current...
5.
Rose J, Yates P, Simpson J, Tischfield J, Stambrook P, Turker M
Cancer Res
. 2000 Jul;
60(13):3404-8.
PMID: 10910047
Heritable gene silencing is an important mechanism of tumor suppressor gene inactivation in a variety of human cancers. In the present study, we show that methylation-associated silencing of the autosomal...
6.
Yates P, Burman R, Mummaneni P, Krussel S, Turker M
J Biol Chem
. 1999 Dec;
274(51):36357-61.
PMID: 10593928
A cis-acting methylation center that signals de novo DNA methylation is located upstream of the mouse Aprt gene. In the current study, two approaches were taken to determine if tandem...
7.
Turker M
Semin Cancer Biol
. 1999 Nov;
9(5):329-37.
PMID: 10547341
Somatic cell DNA methylation patterns in mammals are established during embryonic development and are then maintained somewhat faithfully for the remainder of the individual's lifetime. Pattern formation can be divided...
8.
Burman R, Popovich B, Jacky P, Turker M
Hum Mol Genet
. 1999 Nov;
8(12):2293-302.
PMID: 10545610
The fragile X syndrome is characterized at the molecular level by expansion and methylation of a CGG trinucleotide repeat located within the FMR1 locus. The tissues of most full mutation...
9.
Burman R, Yates P, Green L, Jacky P, Turker M, Popovich B
Am J Hum Genet
. 1999 Oct;
65(5):1375-86.
PMID: 10521303
The vast majority of fragile-X full mutations are heavily methylated throughout the expanded CGG repeat and the surrounding CpG island. Hypermethylation initiates and/or stabilizes transcriptional inactivation of the FMR1 gene,...
10.
Turker M, Gage B, Rose J, Ponomareva O, Tischfield J, Stambrook P, et al.
Cancer Res
. 1999 Oct;
59(19):4781-3.
PMID: 10519383
The presence of increased frequencies of blood-derived and solid tumors in ataxia-telangiectasia (A-T) patients, coupled with a role for the ATM (A-T mutation) protein in detecting specific forms of DNA...