M Ruth Pazos
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Explore the profile of M Ruth Pazos including associated specialties, affiliations and a list of published articles.
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Articles
21
Citations
1022
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Recent Articles
1.
Fanton L, Loria F, Amores M, Pazos M, Adan C, Garcia-Munoz R, et al.
Sci Rep
. 2022 May;
12(1):7895.
PMID: 35551497
Studies have shown that anodically grown TiO nanotubes (TNTs) exhibit excellent biocompatibility. However, TiO nanowires (TNWs) have received less attention. The objective of this study was to investigate the proliferation...
2.
Ceprian M, Vargas C, Garcia-Toscano L, Penna F, Jimenez-Sanchez L, Achicallende S, et al.
Front Pharmacol
. 2019 Oct;
10:1131.
PMID: 31611802
Neonatal hypoxia-ischemia (HI) is a risk factor for myelination disturbances, a key factor for cerebral palsy. Cannabidiol (CBD) protects neurons and glial cells after HI insult in newborn animals. We...
3.
Barata L, Cabanas A, Lafuente H, Vargas C, Ceprian M, Campa L, et al.
Pediatr Res
. 2019 Jan;
85(4):539-545.
PMID: 30675020
Background: Newborn pigs offer theoretical advantages for studying newborn hypoxic-ischemic (HI) brain damage because of a development and structure similar to the human brain. However, the correlation between functional features...
4.
Aparicio N, Grande M, de Martin Esteban S, Lopez A, Ruiz-Perez G, Amores M, et al.
Biochem Pharmacol
. 2018 Sep;
157:202-209.
PMID: 30195729
The search for novel therapies for the treatment of Alzheimer's disease is an urgent need, due to the current paucity of available pharmacological tools and the recent failures obtained in...
5.
Lopez A, Aparicio N, Pazos M, Grande M, Barreda-Manso M, Benito-Cuesta I, et al.
J Neuroinflammation
. 2018 May;
15(1):158.
PMID: 29793509
Background: Because of their low levels of expression and the inadequacy of current research tools, CB cannabinoid receptors (CBR) have been difficult to study, particularly in the brain. This receptor...
6.
Garcia C, Gomez-Canas M, Burgaz S, Palomares B, Gomez-Galvez Y, Palomo-Garo C, et al.
J Neuroinflammation
. 2018 Jan;
15(1):19.
PMID: 29338785
Background: Neuroprotection with cannabinoids in Parkinson's disease (PD) has been afforded predominantly with antioxidant or anti-inflammatory cannabinoids. In the present study, we investigated the anti-inflammatory and neuroprotective properties of VCE-003.2,...
7.
Mohammed N, Ceprian M, Jimenez L, Pazos M, Martinez-Orgado J
CNS Neurol Disord Drug Targets
. 2016 Oct;
16(1):102-108.
PMID: 27686886
Background: A relevant therapeutic time window (TTW) is an important criterion for considering the clinical relevance of a substance preventing newborn hypoxic-ischemic (HI) brain damage. Objective: To test the TTW...
8.
Deiana V, Gomez-Canas M, Pazos M, Fernandez-Ruiz J, Asproni B, Cichero E, et al.
Eur J Med Chem
. 2016 Feb;
112:66-80.
PMID: 26890113
Previous studies have investigated the relevance and structure-activity relationships (SARs) of pyrazole derivatives in relation with cannabinoid receptors, and the series of tricyclic 1,4-dihydroindeno[1,2-c]pyrazoles emerged as potent CB2 receptor ligands....
9.
Del Rio C, Navarrete C, Collado J, Bellido M, Gomez-Canas M, Pazos M, et al.
Sci Rep
. 2016 Feb;
6:21703.
PMID: 26887982
Scleroderma is a group of rare diseases associated with early and transient inflammation and vascular injury, followed by fibrosis affecting the skin and multiple internal organs. Fibroblast activation is the...
10.
Morales P, Whyte L, Chicharro R, Gomez-Canas M, Pazos M, Goya P, et al.
J Med Chem
. 2016 Jan;
59(5):1840-53.
PMID: 26789378
The orphan G protein-coupled receptor GPR55 has been proposed as a novel receptor of the endocannabinoid system. However, the validity of this categorization is still under debate mainly because of...