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M Romkes

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Articles 28
Citations 605
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Recent Articles
1.
Bogen D, Perel J, Helsel J, Hanusa B, Romkes M, Nukui T, et al.
Psychopharmacology (Berl) . 2012 Aug; 225(2):441-51. PMID: 22926004
Rationale: Limited pharmacological data are available to guide methadone treatment during pregnancy and postpartum. Objectives: Study goals were to (1) characterize changes in methadone dose across childbearing, (2) determine enantiomer-specific...
2.
Mullins M, Pochini C, McCrindle S, Romkes M, Safe S, Safe L
Environ Sci Technol . 2012 Jan; 18(6):468-76. PMID: 22247951
No abstract available.
3.
Argiris A, Karamouzis M, Smith R, Kotsakis A, Gibson M, Lai S, et al.
Ann Oncol . 2011 Mar; 22(11):2482-2488. PMID: 21363880
Background: We studied the combination of pemetrexed, a multi-targeted antifolate, and cetuximab, an mAb against the epidermal growth factor receptor, with radiotherapy in poor prognosis head and neck cancer. Patients...
4.
Persad R, Fleming C, Chern H, Lesnick T, Collins C, Smith P, et al.
Urol Oncol . 2011 Jan; 3(1):18-26. PMID: 21227048
The dapsone recovery ratio (DPRR), which is determined after single oral dose administration of dapsone by measuring the parent drug and hydroxylated metabolite, provides an in vivo measure of the...
5.
Johnson H, Han K, Capitano B, Blisard D, Husain S, Linden P, et al.
Antimicrob Agents Chemother . 2009 Nov; 54(2):852-9. PMID: 19933807
The objective of this study was to evaluate the pharmacokinetics of voriconazole and the potential correlations between pharmacokinetic parameters and patient variables in liver transplant patients on a fixed-dose prophylactic...
6.
Zgheib N, Frye R, Tracy T, Romkes M, Branch R
Br J Clin Pharmacol . 2006 Oct; 63(4):477-87. PMID: 17054666
Aims: We investigated flurbiprofen pharmacokinetics in 12 volunteers to develop a phenotypic trait measure that correlates with the fractional clearance to 4'-hydroxyflurbiprofen. The effect of the CYP2C9 inhibitor fluconazole on...
7.
Raimondi S, Paracchini V, Autrup H, Barros-Dios J, Benhamou S, Boffetta P, et al.
Am J Epidemiol . 2006 Sep; 164(11):1027-42. PMID: 17000715
Lung cancer is the most common malignancy in the Western world, and the main risk factor is tobacco smoking. Polymorphisms in metabolic genes may modulate the risk associated with environmental...
8.
Raimondi S, Benhamou S, Coutelle C, Garte S, Hayes R, Kiemeney L, et al.
Biomarkers . 2004 Sep; 9(2):180-9. PMID: 15370874
The objectives were to study the association between metabolic genes involved in alcohol metabolism (CYP2E1 RsaI, CYP2E1 DraI, ADH1C, NQO1) and alcohol consumption in a large sample of healthy controls....
9.
Taioli E, Gaspari L, Benhamou S, Boffetta P, Brockmoller J, Butkiewicz D, et al.
Int J Epidemiol . 2003 Apr; 32(1):60-3. PMID: 12690010
Background: A genetic component of early-onset lung cancer has been suggested. The role of metabolic gene polymorphisms has never been studied in young lung cancer cases. Phase 1 and Phase...
10.
Garte S, Gaspari L, Alexandrie A, Ambrosone C, Autrup H, Autrup J, et al.
Cancer Epidemiol Biomarkers Prev . 2001 Dec; 10(12):1239-48. PMID: 11751440
Using the International Project on Genetic Susceptibility to Environmental Carcinogens (GSEC) database containing information on over 15,000 control (noncancer) subjects, the allele and genotype frequencies for many of the more...