M R Ahmadian
Overview
Explore the profile of M R Ahmadian including associated specialties, affiliations and a list of published articles.
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Articles
31
Citations
1774
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Recent Articles
1.
Boppudi S, Bogershausen N, Hove H, Percin E, Aslan D, Dvorsky R, et al.
Clin Genet
. 2016 Mar;
90(4):334-42.
PMID: 26970110
Oculoectodermal syndrome (OES) and encephalocraniocutaneous lipomatosis (ECCL) are rare disorders that share many common features, such as epibulbar dermoids, aplasia cutis congenita, pigmentary changes following Blaschko lines, bony tumor-like lesions,...
2.
Dutting S, Heidenreich J, Cherpokova D, Amin E, Zhang S, Ahmadian M, et al.
J Thromb Haemost
. 2015 Jan;
13(5):827-38.
PMID: 25628054
Background: Platelet aggregation at sites of vascular injury is essential for normal hemostasis, but may also cause pathologic vessel occlusion. Rho GTPases are molecular switches that regulate essential cellular processes,...
3.
Linka R, Risse S, Bienemann K, Werner M, Linka Y, Krux F, et al.
Leukemia
. 2012 Feb;
26(5):963-71.
PMID: 22289921
The purpose of this study was the appraisal of the clinical and functional consequences of germline mutations within the gene for the IL-2 inducible T-cell kinase, ITK. Among patients with...
4.
Stark Z, Gillessen-Kaesbach G, Ryan M, Cirstea I, Gremer L, Ahmadian M, et al.
Clin Genet
. 2011 Jul;
81(6):590-4.
PMID: 21797849
Noonan and Cardio-facio-cutaneous (CFC) syndromes are characterized by typical dysmorphic features, cardiac defects, short stature, variable ectodermal anomalies, and intellectual disability. Both belong to the Ras/mitogen-activated protein kinase pathway group...
5.
Schmidt S, Schneider L, Essmann F, Cirstea I, Kuck F, Kletke A, et al.
Oncogene
. 2010 Aug;
29(46):6184-92.
PMID: 20729911
Microtubule-interfering cancer drugs such as paclitaxel (PTX) often cause chemoresistance and severe side effects, including neurotoxicity. To explore potentially novel antineoplastic molecular targets, we investigated the cellular response of breast...
6.
Scheffzek K, Ahmadian M
Cell Mol Life Sci
. 2005 Nov;
62(24):3014-38.
PMID: 16314935
The conversion of guanosine triphosphate (GTP) to guanosine diphosphate (GDP) and inorganic phosphate (P(i)) by guanine nucleotide binding proteins (GNBPs) is a fundamental process in living cells and represents an...
7.
Rose R, Weyand M, Lammers M, Ishizaki T, Ahmadian M, Wittinghofer A
Nature
. 2005 May;
435(7041):513-8.
PMID: 15864301
Formins are involved in a variety of cellular processes that require the remodelling of the cytoskeleton. They contain formin homology domains FH1 and FH2, which initiate actin assembly. The Diaphanous-related...
8.
GAIL R, Costisella B, Ahmadian M, Wittinghofer A
Chembiochem
. 2002 Feb;
2(7-8):570-5.
PMID: 11828490
The small guanosine triphosphate (GTP) binding protein Ras is involved in many cellular signal transduction processes leading to cell growth, differentiation and apoptosis. Mutations in ras genes are found in...
9.
Allin C, Ahmadian M, Wittinghofer A, Gerwert K
Proc Natl Acad Sci U S A
. 2001 Jul;
98(14):7754-9.
PMID: 11438727
The molecular reaction mechanism of the GTPase-activating protein (GAP)-catalyzed GTP hydrolysis by Ras was investigated by time resolved Fourier transform infrared (FTIR) difference spectroscopy using caged GTP (P(3)-1-(2-nitro)phenylethyl guanosine 5'-O-triphosphate)...
10.
Demunter A, Ahmadian M, Libbrecht L, Stas M, Baens M, Scheffzek K, et al.
Cancer Res
. 2001 Jun;
61(12):4916-22.
PMID: 11406571
Mutations in the ras gene are key events in the process of carcinogenesis; in particular, point mutations in codon 61 of exon 2 of the N-ras gene occur frequently in...