M P Charlton
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Explore the profile of M P Charlton including associated specialties, affiliations and a list of published articles.
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74
Citations
2599
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Recent Articles
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Silverman-Gavrila L, Senzel A, Charlton M, Feng Z
Neuroscience
. 2011 May;
186:94-109.
PMID: 21530618
Long-term memory formation requires "de novo" expression and post-translational modification of many proteins. Understanding the temporal and spatial regulatory pattern of these proteins is fundamental to decoding the molecular basis...
3.
Charlton M, Atwood H
Neurosci Lett
. 2009 Jul;
5(3-4):165-9.
PMID: 19604988
The giant synapse of the squid was tested with small amplitude, long-lasting depolarizations applied to the presynaptic terminal. The presynaptic potential at which transmitter release could be detected was only...
4.
Silverman-Gavrila L, Lu T, Prashad R, Nejatbakhsh N, Charlton M, Feng Z
Neuroscience
. 2009 Mar;
161(2):621-34.
PMID: 19324076
Chronic hypoxia is a common clinical event that induces adaptive responses and can result in behavioral deterioration. The reduction of metabolic rate during hypoxia may limit overall protein phosphorylation owing...
5.
Carmichael N, Dostrovsky J, Charlton M
Neuroscience
. 2008 Apr;
153(3):832-41.
PMID: 18420352
Activation of nociceptors causes them to secrete neuropeptides. The binding of these peptides to receptors on blood vessels causes vasodilation and increased vascular permeability that allows loss of proteins and...
6.
Macleod G, Chen L, Karunanithi S, Peloquin J, Atwood H, McRory J, et al.
Eur J Neurosci
. 2006 Jul;
23(12):3230-44.
PMID: 16820014
Voltage-gated Ca2+ channels in nerve terminals open in response to action potentials and admit Ca2+, the trigger for neurotransmitter release. The cacophony gene encodes the primary presynaptic voltage-gated Ca2+ channel...
7.
Macleod G, Suster M, Charlton M, Atwood H
J Neurosci Methods
. 2003 Aug;
127(2):167-78.
PMID: 12906946
Although the Drosophila larva has been extensively used for genetic studies of synaptic transmission and locomotion, neurophysiological studies have lagged because it is difficult to investigate circuitry and synaptic function...
8.
Macleod G, Charlton M, Atwood H
J Neurophysiol
. 2002 Nov;
88(5):2659-63.
PMID: 12424301
Drosophila is a powerful model for neuroscientists, but physiological techniques have not kept pace with advances in molecular genetics. We introduce a reliable assay for intracellular calcium dynamics in Drosophila...
9.
Tsang C, Elrick D, Charlton M
J Neurosci
. 2000 Jan;
20(23):8685-92.
PMID: 11102474
alpha-Latrotoxin (alpha-LTX) is a neurotoxin that accelerates spontaneous exocytosis independently of extracellular Ca(2+). Although alpha-LTX increases spontaneous transmitter release at synapses, the mechanism is unknown. We tested the hypothesis that...
10.
Elrick D, Charlton M
J Neurophysiol
. 1999 Dec;
82(6):3550-62.
PMID: 10601481
alpha-latrocrustatoxin (alpha-LCTX), a component of black widow spider venom (BWSV), produced a 50-fold increase in the frequency of spontaneously occurring miniature excitatory postsynaptic potentials (mEPSPs) at crayfish neuromuscular junctions but...