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G J Augustine

Explore the profile of G J Augustine including associated specialties, affiliations and a list of published articles. Areas
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Articles 89
Citations 4636
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Recent Articles
1.
Tantra M, Guo L, Kim J, Zainolabidin N, Eulenburg V, Augustine G, et al.
Genes Brain Behav . 2018 Feb; 17(6):e12466. PMID: 29446202
Inhibitory interneurons mediate the gating of synaptic transmission and modulate the activities of neural circuits. Disruption of the function of inhibitory networks in the forebrain is linked to impairment of...
2.
Kuner T, Li Y, Gee K, Bonewald L, Augustine G
Proc Natl Acad Sci U S A . 2008 Jan; 105(1):347-52. PMID: 18172208
The time at which the N-ethylmaleimide-sensitive factor (NSF) acts during synaptic vesicle (SV) trafficking was identified by time-controlled perturbation of NSF function with a photoactivatable inhibitory peptide. Photolysis of this...
3.
Wang H, Peca J, Matsuzaki M, Matsuzaki K, Noguchi J, Qiu L, et al.
Proc Natl Acad Sci U S A . 2007 May; 104(19):8143-8. PMID: 17483470
To permit rapid optical control of brain activity, we have engineered multiple lines of transgenic mice that express the light-activated cation channel Channelrhodopsin-2 (ChR2) in subsets of neurons. Illumination of...
4.
Augustine G, Morgan J, Villalba-Galea C, Jin S, Prasad K, Lafer E
Biochem Soc Trans . 2006 Jan; 34(Pt 1):68-72. PMID: 16417485
The role of clathrin-mediated endocytosis in SV (synaptic vesicle) recycling has been studied by combining molecular biology, physiology and electron microscopy at the squid giant synapse. Procedures that prevent clathrin...
5.
Augustine G
Nat Neurosci . 2001 Nov; 4(11):1051-2. PMID: 11687808
No abstract available.
6.
Morgan J, Prasad K, Jin S, Augustine G, Lafer E
Neuron . 2001 Oct; 32(2):289-300. PMID: 11683998
We have examined the roles of Hsc70 and auxilin in the uncoating of clathrin-coated vesicles (CCVs) during neuronal endocytosis. We identified two peptides that inhibit the ability of Hsc70 and...
7.
Nishiki T, Augustine G
J Comp Neurol . 2001 Jun; 436(1):1-3. PMID: 11413541
No abstract available.
8.
Augustine G
Curr Opin Neurobiol . 2001 Jun; 11(3):320-6. PMID: 11399430
Recent work has established that different geometric arrangements of calcium channels are found at different presynaptic terminals, leading to a wide spectrum of calcium signals for triggering neurotransmitter release. These...
9.
Morgan J, Lafer E, Augustine G
Neuron . 2001 May; 30(1):5-7. PMID: 11343637
No abstract available.
10.
Tokumaru H, Umayahara K, Pellegrini L, Ishizuka T, Saisu H, Betz H, et al.
Cell . 2001 Mar; 104(3):421-32. PMID: 11239399
Synaphin/complexin is a cytosolic protein that preferentially binds to syntaxin within the SNARE complex. We find that synaphin promotes SNAREs to form precomplexes that oligomerize into higher order structures. A...