M Osman Sheikh
Overview
Explore the profile of M Osman Sheikh including associated specialties, affiliations and a list of published articles.
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Articles
22
Citations
348
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Recent Articles
1.
Byrne B, Parenti G, Schoser B, van der Ploeg A, Do H, Fox B, et al.
Front Neurol
. 2025 Jan;
15():1540452.
PMID: 39830206
[This corrects the article DOI: 10.3389/fneur.2024.1451512.].
2.
Byrne B, Parenti G, Schoser B, van der Ploeg A, Do H, Fox B, et al.
Front Neurol
. 2024 Nov;
15():1451512.
PMID: 39494167
Enzyme replacement therapy (ERT) is the only approved disease-modifying treatment modality for Pompe disease, a rare, inherited metabolic disorder caused by a deficiency in the acid -glucosidase (GAA) enzyme that...
3.
Sheikh M, Capicciotti C, Olivier-Van Stichelen S
Front Mol Biosci
. 2022 Sep;
9:1012485.
PMID: 36158575
No abstract available.
4.
Boland A, Gas-Pascual E, Nottingham B, van der Wel H, Daniel N, Sheikh M, et al.
J Biol Chem
. 2022 Aug;
298(9):102305.
PMID: 35933019
E3-SCF (Skp1/cullin-1/F-box protein) polyubiquitin ligases activate the proteasomal degradation of over a thousand proteins, but the evolutionary diversification of the F-box protein (FBP) family of substrate receptor subunits has challenged...
5.
Sheikh M, Capicciotti C, Liu L, Praissman J, Ding D, Mead D, et al.
Nat Commun
. 2022 Jun;
13(1):3617.
PMID: 35750689
α-Dystroglycan (α-DG) is uniquely modified on O-mannose sites by a repeating disaccharide (-Xylα1,3-GlcAβ1,3-) termed matriglycan, which is a receptor for laminin-G domain-containing proteins and employed by old-world arenaviruses for infection....
6.
Selvan N, Mehta N, Venkateswaran S, Brignol N, Graziano M, Sheikh M, et al.
J Biol Chem
. 2021 May;
296:100769.
PMID: 33971197
Acid alpha-glucosidase (GAA) is a lysosomal glycogen-catabolizing enzyme, the deficiency of which leads to Pompe disease. Pompe disease can be treated with systemic recombinant human GAA (rhGAA) enzyme replacement therapy...
7.
Kurz S, Sheikh M, Lu S, Wells L, Tiemeyer M
Mol Cell Proteomics
. 2020 Dec;
20:100045.
PMID: 33376194
HPLC has been employed for decades to enhance detection sensitivity and quantification of complex analytes within biological mixtures. Among these analytes, glycans released from glycoproteins and glycolipids have been characterized...
8.
Mandalasi M, Kim H, Thieker D, Sheikh M, Gas-Pascual E, Rahman K, et al.
J Biol Chem
. 2020 May;
295(27):9223-9243.
PMID: 32414843
Skp1, a subunit of E3 Skp1/Cullin-1/F-box protein ubiquitin ligases, is modified by a prolyl hydroxylase that mediates O regulation of the social amoeba and the parasite The full effect of...
9.
Sheikh M, Venzke D, Anderson M, Yoshida-Moriguchi T, Glushka J, Nairn A, et al.
Glycobiology
. 2020 Mar;
30(10):817-829.
PMID: 32149355
Mutations in multiple genes required for proper O-mannosylation of α-dystroglycan are causal for congenital/limb-girdle muscular dystrophies and abnormal brain development in mammals. Previously, we and others further elucidated the functional...
10.
Sandoval D, Gomez Toledo A, Painter C, Tota E, Sheikh M, West A, et al.
J Biol Chem
. 2020 Jan;
295(9):2804-2821.
PMID: 31964714
Animal cells express heparan sulfate proteoglycans that perform many important cellular functions by way of heparan sulfate-protein interactions. The identification of membrane heparan sulfate-binding proteins is challenging because of their...