M Michele Pisano
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Explore the profile of M Michele Pisano including associated specialties, affiliations and a list of published articles.
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73
Citations
749
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Recent Articles
1.
Seelan R, Greene R, Pisano M
Microrna
. 2023 Nov;
12(3):171-176.
PMID: 38009000
Different modes of gene regulation, such as histone modification, transcription factor binding, DNA methylation, and microRNA (miRNA) expression, are critical for the spatiotemporal expression of genes in developing orofacial tissues....
2.
Mukhopadhyay P, Seelan R, Greene R, Pisano M
Microrna
. 2022 Oct;
12(1):63-81.
PMID: 36200240
Background: Neural tube (NT) morphogenesis is reliant on the proper temporospatial expression of numerous genes and synchronized crosstalk between diverse signaling cascades and gene regulatory networks governing key cellular processes....
3.
Seelan R, Pisano M, Greene R
Microrna
. 2022 Feb;
11(1):2-11.
PMID: 35168515
It is estimated that 2-4% of live births will have a birth defect (BD). The availability of biomarkers for the prenatal detection of BDs will facilitate early risk assessment, prompt...
4.
Seelan R, Pisano M, Greene R
Differentiation
. 2022 Feb;
124:1-16.
PMID: 35144134
Environmental and genetic factors contribute significantly to the etiology of orofacial clefting, which is one of the most common of human congenital craniofacial malformations. Current biological thought now recognizes that...
5.
Mukhopadhyay P, Smolenkova I, Seelan R, Pisano M, Greene R
Cleft Palate Craniofac J
. 2021 Nov;
60(1):27-38.
PMID: 34730446
Objective: Normal development of the embryonic orofacial region requires precise spatiotemporal coordination between numerous genes. MicroRNAs represent small, single-stranded, non-coding molecules that regulate gene expression. This study examines the role...
6.
Mukhopadhyay P, Greene R, Pisano M
Cell Biochem Funct
. 2020 Mar;
38(7):905-920.
PMID: 32129905
MicroRNAs (miRNAs) provide context-dependent transcriptional regulation of genes comprising signalling networks throughout the developing organism including morphogenesis of the embryonic neural tube (NT). Using a high-sensitivity, high-coverage microarray analysis platform,...
7.
Greene R, Pisano M
Birth Defects Res
. 2019 Aug;
111(17):1294-1301.
PMID: 31400084
Maternal smoking during pregnancy represents a major public health concern increasing the risk for low birth weight, congenital anomalies, preterm birth, fetal mortality, and morbidity. In an effort to diminish...
8.
Mukhopadhyay P, Seelan R, Greene R, Pisano M
Reprod Toxicol
. 2019 Apr;
86:76-85.
PMID: 30953684
Prenatal exposure to arsenic, a naturally occurring toxic element, causes neural tube defects (NTDs) and, in animal models, orofacial anomalies. Since aberrant development or migration of cranial neural crest cells...
9.
Seelan R, Mukhopadhyay P, Pisano M, Greene R
Drug Metab Rev
. 2018 Feb;
50(2):193-207.
PMID: 29455551
5-Aza-2'-deoxycytidine (AzaD), also known as Decitabine, is a deoxycytidine analog that is typically used to activate methylated and silenced genes by promoter demethylation. However, a survey of the scientific literature...
10.
Seelan R, Mukhopadhyay P, Warner D, Smolenkova I, Pisano M, Greene R
Reprod Toxicol
. 2016 Dec;
67:100-110.
PMID: 27923600
Defects in development of the secondary palate, which arise from the embryonic first branchial arch (1-BA), can cause cleft palate (CP). Administration of 5-Aza-2'-deoxycytidine (AzaD), a demethylating agent, to pregnant...