M Loyevsky
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Explore the profile of M Loyevsky including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Epstein J, Tewari K, Lyke K, Sim B, Billingsley P, Laurens M, et al.
Science
. 2011 Sep;
334(6055):475-80.
PMID: 21903775
Our goal is to develop a vaccine that sustainably prevents Plasmodium falciparum (Pf) malaria in ≥80% of recipients. Pf sporozoites (PfSPZ) administered by mosquito bites are the only immunogens shown...
2.
Walcourt A, Kurantsin-Mills J, Adenuga B, Loyevsky M, KASSIM O, Gordeuk V
Exp Parasitol
. 2008 Oct;
120(4):381-4.
PMID: 18823976
The presence of sickle hemoglobin causes accumulation of hemoglobin degradative products that favor oxidative reaction in erythrocytes. Artemisinin derivatives exert antiparasite effects through oxidative reactions within infected erythrocytes. Using [(3)H]-hypoxanthine...
3.
Goudeau C, Loyevsky M, KASSIM O, Gordeuk V, Nick H
Br J Haematol
. 2002 Feb;
115(4):918-23.
PMID: 11843826
We tested in vitro the antimalarial properties of ICL670A, a newly developed iron chelator for the long-term oral treatment of iron overload. Ring-stage synchronized cultures of Plasmodium falciparum cultured in...
4.
Loyevsky M, LaVaute T, Allerson C, Stearman R, KASSIM O, Cooperman S, et al.
Blood
. 2001 Oct;
98(8):2555-62.
PMID: 11588054
This study cloned and sequenced the complementary DNA (cDNA) encoding of a putative malarial iron responsive element-binding protein (PfIRPa) and confirmed its identity to the previously identified iron-regulatory protein (IRP)-like...
5.
Deharo E, Loyevsky M, John C, Balanza E, Ruiz G, Munoz V, et al.
Exp Parasitol
. 2000 Jun;
94(3):198-200.
PMID: 10831386
Three compounds of an aminothiol family of iron chelators were examined for activity against trypomastigote (human) and epimastigote (vector) forms of Trypanosoma cruzi: tetraethyl and tetramethyl derivatives of ethane-1,2-bis (N-1-amino-3-ethyl...
6.
Looker A, Loyevsky M, Gordeuk V
Clin Chem
. 1999 Dec;
45(12):2191-9.
PMID: 10585352
Background: Serum transferrin receptor (sTfR) concentrations are increased in iron deficiency. We wished to examine whether they are decreased in the presence of potential iron-loading conditions, as reflected by increased...
7.
Weiss G, Umlauft F, Urbanek M, Herold M, Loyevsky M, Lovevsky M, et al.
J Infect Dis
. 1999 Oct;
180(5):1452-8.
PMID: 10515803
We studied the associations of macrophage activity, T-helper cell types 1 and 2 (Th-1/Th-2) responses, and iron status in 55 patients with hepatitis C virus (HCV)-related liver disease and 28...
8.
Loyevsky M, John C, Dickens B, Hu V, Miller J, Gordeuk V
Mol Biochem Parasitol
. 1999 Jul;
101(1-2):43-59.
PMID: 10413042
To examine the site of action of antimalarial iron chelators, iron ligands were added to control erythrocytes and to erythrocytes parasitized with Plasmodium falciparum, and the concentration of intracellular labile...
9.
Gangaidzo I, Moyo V, Saungweme T, Khumalo H, Charakupa R, Gomo Z, et al.
Gut
. 1999 Jul;
45(2):278-83.
PMID: 10403742
Background: In a previously described model, heterozygotes for an African iron loading locus develop iron overload only when dietary iron is high, but homozygotes may do so with normal dietary...
10.
Mabeza G, Loyevsky M, Gordeuk V, Weiss G
Pharmacol Ther
. 1999 Mar;
81(1):53-75.
PMID: 10051178
Malaria is one of the major global health problems, and an urgent need for the development of new antimalarial agents faces the scientific community. A considerable number of iron(III) chelators,...