M Leippe
Overview
Explore the profile of M Leippe including associated specialties, affiliations and a list of published articles.
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Articles
46
Citations
823
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Recent Articles
1.
Cauchard S, Van Reet N, Buscher P, Goux D, Grotzinger J, Leippe M, et al.
Antimicrob Agents Chemother
. 2016 Jan;
60(5):2610-9.
PMID: 26824936
Trypanozoon parasites infect both humans, causing sleeping sickness, and animals, causing nagana, surra, and dourine. Control of nagana and surra depends to a great extent on chemotherapy. However, drug resistance...
2.
Di Bella M, Fedders H, De Leo G, Leippe M
Results Immunol
. 2013 Dec;
1(1):70-5.
PMID: 24371555
Tunicates comprising a wide variety of different species synthesize antimicrobial peptides as important effector molecules of the innate immune system. Recently, two putative gene families coding for antimicrobial peptides were...
3.
Bruhn O, Cauchard J, Schlusselhuber M, Gelhaus C, Podschun R, Thaller G, et al.
Vet Immunol Immunopathol
. 2009 Feb;
130(1-2):102-6.
PMID: 19211153
Defensins are small effector molecules of the innate immune system, synthesised by various organisms including plants and animals. The peptides act as endogenous antibiotics with an antimicrobial activity against a...
4.
Clark C, Alsmark U, Tazreiter M, Saito-Nakano Y, Ali V, Marion S, et al.
Adv Parasitol
. 2007 Dec;
65:51-190.
PMID: 18063096
The intestinal parasite Entamoeba histolytica is one of the first protists for which a draft genome sequence has been published. Although the genome is still incomplete, it is unlikely that...
5.
Bruhn H, Leippe M
Zoology (Jena)
. 2005 Dec;
104(1):3-11.
PMID: 16351813
Amoebae may be viewed as primitive, actively phagocytosing eukaryotic cells, many of which use bacteria as a major nutrient source. At a very archaic level, amoebae exert mechanisms which kill...
6.
Hellberg A, Nowak N, Leippe M, Tannich E, Bruchhaus I
Protein Expr Purif
. 2002 Jan;
24(1):131-7.
PMID: 11812234
Cysteine proteinases and in particular cysteine proteinase 5 (EhCP5) of Entamoeba histolytica are considered important for ameba pathogenicity. To study EhCP5 in more detail a protocol was elaborated to produce...
7.
Bruhn H, Leippe M
Biochim Biophys Acta
. 2001 Aug;
1514(1):14-20.
PMID: 11513801
Amoebapores, the pore-forming proteins of Entamoeba histolytica, have been shown to play a pivotal role in the pathogenicity of the protozoan parasite. They belong to the functionally diverse family of...
8.
Andra J, Berninghausen O, Leippe M
Med Microbiol Immunol
. 2001 Jun;
189(3):169-73.
PMID: 11388616
Natural products are the major source of lead compounds for drugs against human pathogens. Among the first natural peptides from animals for which a potent antibacterial activity has been recognized...
9.
Ebert F, Guillen N, Leippe M, Tannich E
Mol Biochem Parasitol
. 2001 Feb;
111(2):459-64.
PMID: 11163453
No abstract available.
10.
Ernst W, Thoma-Uszynski S, Teitelbaum R, Ko C, HANSON D, Clayberger C, et al.
J Immunol
. 2000 Dec;
165(12):7102-8.
PMID: 11120840
Granulysin, a protein located in the acidic granules of human NK cells and cytotoxic T cells, has antimicrobial activity against a broad spectrum of microbial pathogens. A predicted model generated...