M L Muhich
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Explore the profile of M L Muhich including associated specialties, affiliations and a list of published articles.
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10
Citations
203
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Recent Articles
1.
Muhich M, Iida C, Horikoshi M, Roeder R, Parker C
Proc Natl Acad Sci U S A
. 1990 Dec;
87(23):9148-52.
PMID: 2123550
Proper initiation of transcription by RNA polymerase II requires the TATA-consensus-binding transcription factor TFIID. A cDNA clone encoding the Drosophila TFIID protein has been isolated and characterized. The deduced amino...
2.
Muhich M, Hsu M, Boothroyd J
Gene
. 1989 Oct;
82(1):169-75.
PMID: 2684772
The synthesis of most, if not all, mRNA in trypanosomes involves the splicing in trans of two RNA molecules. One of these includes the common 5' mini-exon or spliced-leader sequence,...
3.
Hsu M, Muhich M, Boothroyd J
Biochemistry
. 1989 Jul;
28(15):6440-6.
PMID: 2551375
We have isolated and characterized a developmentally regulated gene in Trypanosoma brucei, arbitrarily termed BS2. BS2 mRNA is substantially more abundant in bloodstream-form trypanosomes than in procyclic culture forms. Its...
4.
Muhich M, Boothroyd J
J Biol Chem
. 1989 May;
264(13):7107-10.
PMID: 2708359
Synthesis of mRNA in trypanosomes involves an apparent trans-splicing reaction whereby a common 39-nucleotide mini-exon sequence is joined to the protein-coding exon of a mRNA precursor. We have previously shown...
5.
Muhich M, Boothroyd J
Mol Cell Biol
. 1988 Sep;
8(9):3837-46.
PMID: 3221866
Maturation of mRNA precursors in trypanosomes involves an apparent trans splicing event in which a 39-nucleotide miniexon sequence, common to all trypanosome mRNAs, is joined to the 5' end of...
6.
Muhich M, Hughes D, Simpson A, Simpson L
Nucleic Acids Res
. 1987 Apr;
15(7):3141-53.
PMID: 3562248
A repeated sequence from the Crithidia fasciculata nuclear genome has been isolated which is homologous to the mini-exon genes of other kinetoplastid protozoa. Sequence analysis of the 417 bp monomeric...
7.
Muhich M, Simpson L
Nucleic Acids Res
. 1986 Jul;
14(13):5531-56.
PMID: 3016649
Multiple sequence classes of kinetoplast minicircle DNA from Leishmania tarentolae were cleaved by mung bean nuclease in the presence of formamide, yielding unit length linear molecules which retained the anomalous...
8.
Simpson A, Neckelmann N, de la Cruz V, Muhich M, Simpson L
Nucleic Acids Res
. 1985 Aug;
13(16):5977-93.
PMID: 2994021
Transcripts for six Leishmania tarentolae maxicircle structural genes (cytochrome oxidase subunits I, II and III, cytochrome b, human mitochondrial unidentified reading frames 4 and 5) and several unidentified open reading...
9.
Muhich M, Neckelmann N, Simpson L
Nucleic Acids Res
. 1985 May;
13(9):3241-60.
PMID: 2987878
A 2.76 kb segment of the 12 kb divergent region of the Leishmania tarentolae kinetoplast maxicircle DNA consists almost entirely of repeated sequences. The repeats can be grouped into six...
10.
Muhich M, Simpson L, Simpson A
Proc Natl Acad Sci U S A
. 1983 Jul;
80(13):4060-4.
PMID: 6306661
The conserved portions of the maxicircle DNAs of Leishmania tarentolae and Trypanosoma brucei are organized in a basically colinear manner over a 15- to 17-kilobase region that is interrupted by...