D E Hughes
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Explore the profile of D E Hughes including associated specialties, affiliations and a list of published articles.
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Articles
164
Citations
2456
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Recent Articles
1.
Srivastava A, Turner J, Hughes D, Griffiths A
Microb Ecol
. 2013 Nov;
11(1):71-9.
PMID: 24221241
A total of 450 yeast isolates were obtained from up to 34 sites on 59 human subjects. The yeasts were characterized using morphological features and assimilation tests. Ten species were...
2.
McIlwain H, Roper J, Hughes D
Biochem J
. 2010 Mar;
41(3):xliii.
PMID: 20266543
No abstract available.
3.
Davies A, Hughes D, Grimer R
Eur Radiol
. 2005 May;
15(10):2194-9.
PMID: 15864595
We retrospectively studied the frequency of persistent foci of fat signal on magnetic resonance (MR) imaging in osteomyelitis to assess its frequency, cause and diagnostic value. The radiographs and MR...
4.
Yu S, Cao W, Kashireddy P, Meyer K, Jia Y, Hughes D, et al.
J Biol Chem
. 2001 Sep;
276(45):42485-91.
PMID: 11551940
Peroxisome proliferators, which function as peroxisome proliferator-activated receptor alpha (PPARalpha) agonists, induce peroxisomal, microsomal, and mitochondrial fatty acid oxidation enzymes, in conjunction with peroxisome proliferation, in liver cells. Sustained activation...
5.
Wilson I, Schiff C, Hughes D, Somerville S
Genetics
. 2001 Jul;
158(3):1301-9.
PMID: 11454776
Powdery mildew diseases are economically important diseases, caused by obligate biotrophic fungi of the Erysiphales. To understand the complex inheritance of resistance to the powdery mildew disease in the model...
6.
Zhou H, Hughes D, Major M, Yoo K, Pesold C, Costa R
Gene Expr
. 2001 Jul;
9(4-5):217-36.
PMID: 11444531
To assess the role of hepatocyte nuclear factor-3beta (HNF-3beta) in hepatocyte-specific gene transcription, we reported the characterization of the liver phenotype with transgenic mice in which the -3-kb transthyretin (TTR)...
7.
Majumdar A, Hughes D, Lichtsteiner S, Wang Z, Lebkowski J, Vasserot A
Gene Ther
. 2001 Apr;
8(7):568-78.
PMID: 11319624
In human cells, telomerase activity is regulated by transcriptional control of the telomerase reverse transcriptase gene (hTERT) whose product is the catalytic subunit of the enzyme. The hTERT promoter is...
8.
Bowen D, Southerland W, Johnson D, Hawkins Jr M, Hughes D
Cancer Detect Prev
. 2000 Dec;
24(5):452-8.
PMID: 11129987
The cytotoxicity of high-dose methotrexate (MTX), 10 and 100 microM, and 5-fluorouracil (5-FU) combinations is independent of sequence in human MDA-MB-436 breast carcinoma cells. The growth inhibitory effects of 10...
9.
Shipman C, Vanderkerken K, Rogers M, Lippitt J, Asosingh K, Hughes D, et al.
Br J Haematol
. 2000 Nov;
111(1):283-6.
PMID: 11091214
Bisphosphonates are effective in the management of bone disease in patients with multiple myeloma and recent reports have suggested that they may also have an anti-tumour activity. In support of...
10.
Nicklin M, Hughes D, Barton J, Ure J, Duff G
J Exp Med
. 2000 Jan;
191(2):303-12.
PMID: 10637274
Branch points and flexures in the high pressure arterial system have long been recognized as sites of unusually high turbulence and consequent stress in humans are foci for atherosclerotic lesions....