M L Hamelink
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Explore the profile of M L Hamelink including associated specialties, affiliations and a list of published articles.
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23
Citations
83
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Recent Articles
1.
Bruijnzeel P, Warringa R, Kok P, Hamelink M, Kreukniet H, Koenderman L
J Allergy Clin Immunol
. 1993 Jul;
92(1 Pt 2):159-64.
PMID: 8393021
Using the allergen-induced late-phase asthmatic reaction as a working model, we studied the activity of certain inflammatory cells and their reaction to nedocromil sodium. The processes that were examined in...
2.
Bruijnzeel P, Hamelink M, Kok P, KREUKNIET J
Br J Pharmacol
. 1989 Mar;
96(3):631-6.
PMID: 2541846
1. Inflammatory cells such as eosinophils and neutrophils are thought to contribute actively to the pathogenesis of asthma by the release of bronchoconstrictor mediators including leukotrienes. Previous studies have revealed...
3.
Bruijnzeel P, Warringa R, Kok P, Hamelink M, KREUKNIET J
Drugs
. 1989 Jan;
37 Suppl 1:9-18; discussion 69-77.
PMID: 2547570
Inflammatory cells, such as neutrophils and eosinophils, are thought to actively contribute to the pathogenesis of asthma since they infiltrate into the lung tissue and may be activated locally to...
4.
Kok P, Hamelink M, Kijne G, Verhagen J, Koenderman L, Veldink G, et al.
Agents Actions
. 1989 Jan;
26(1-2):96-8.
PMID: 2496595
Addition of arachidonic acid (50 microM) to purified human eosinophils leads to the formation of considerable amounts of LTC4 [11.3 +/- 1.3) x 10(6) molecules/cell, mean +/- SEM, n =...
5.
Koenderman L, Kok P, Hamelink M, Verhoeven A, Bruijnzeel P
J Leukoc Biol
. 1988 Aug;
44(2):79-86.
PMID: 3404069
A simple and improved procedure is described for the isolation of human eosinophils from normal individuals with about 2% eosinophils in their peripheral blood. This method comprises a preincubation of...
6.
Kok P, Hamelink M, Kijne A, Verhagen J, Koenderman L, Bruynzeel P
Biochem Biophys Res Commun
. 1988 Jun;
153(2):676-82.
PMID: 3132917
Stimulation of purified human eosinophils with 50 microM arachidonic acid leads to the production of leukotriene C4, 15-hydroxy-eicosatetraenoic acid and 15-series leukotrienes. The ratio of the amounts of leukotriene C4...
7.
van der Vet A, KREUKNIET J, Drost R, Maes R, Fokkens J, Hamelink M
Int J Clin Pharmacol Ther Toxicol
. 1987 Nov;
25(11):609-12.
PMID: 2828250
In a group of ten patients with chronic asthmatic bronchitis, a good improvement of the lung function was achieved by a sustained-release terbutaline preparation (Bricanyl Retard) in a dosage of...
8.
Bruijnzeel P, Kok P, Hamelink M, Kijne A, Verhagen J
Prostaglandins
. 1987 Aug;
34(2):205-14.
PMID: 3118415
Platelet-activating factor, at a concentration of 10 microM, was capable of inducing leukotriene C4 synthesis by eosinophils of healthy donors, i.e. (3.1 +/- 0.3) x 10(6) molecules leukotriene C4/cell (n...
9.
Bruijnzeel P, Hamelink M, Prins K, Remmert G, Meyling F
Ann Allergy
. 1987 Mar;
58(3):179-82.
PMID: 3493716
Blood leukocyte numbers and proportions of T lymphocyte subsets were studied in extrinsic asthmatics (EA), intrinsic asthmatics (IA), IA systemically treated with corticosteroids (IA + C), and in age-matched control...
10.
van der Vet A, KREUKNIET J, Drost R, Maes R, Fokkens J, Hamelink M
Int J Clin Pharmacol Ther Toxicol
. 1986 Nov;
24(11):638-42.
PMID: 3025113
After one week theophylline therapy with a sustained release preparation (TheoDur 200 and 300 mg), a mean theophylline level of 10 mg/l was obtained in a group of ten patients...