M Kielman
Overview
Explore the profile of M Kielman including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
505
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0
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Recent Articles
1.
Ridanpaa M, Fodde R, Kielman M
Mech Dev
. 2001 Dec;
109(2):173-81.
PMID: 11731231
Beta-catenin has a dual role in the cell. At the membrane, it connects E-cadherin to the actin cytoskeleton, while in the nucleus, it controls gene expression in concert with Tcf-like...
2.
Fodde R, Kuipers J, Rosenberg C, Smits R, Kielman M, Gaspar C, et al.
Nat Cell Biol
. 2001 Apr;
3(4):433-8.
PMID: 11283620
Two forms of genetic instability have been described in colorectal cancer: microsatellite instability and chromosomal instability. Microsatellite instability results from mutations in mismatch repair genes; chromosomal instability is the hallmark...
3.
Fodde R, Smits R, Hofland N, Kielman M, Meera Khan P
Cytogenet Cell Genet
. 1999 Nov;
86(2):105-11.
PMID: 10545699
Colorectal cancer still represents one of the most common causes of morbidity and mortality among Western populations. The adenomatous polyposis coli (APC) gene, originally identified as the gene responsible for...
4.
Wielenga V, Smits R, Korinek V, Smit L, Kielman M, Fodde R, et al.
Am J Pathol
. 1999 Feb;
154(2):515-23.
PMID: 10027409
Overexpression of cell surface glycoproteins of the CD44 family is an early event in the colorectal adenoma-carcinoma sequence. This suggests a link with disruption of APC tumor suppressor protein-mediated regulation...