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J H Van Es

Explore the profile of J H Van Es including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 599
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Recent Articles
1.
Daly C, Shaw P, Ordonez L, Williams G, Quist J, Grigoriadis A, et al.
Oncogene . 2024 Jan; 43(12):918. PMID: 38263250
No abstract available.
2.
Daly C, Shaw P, Ordonez L, Williams G, Quist J, Grigoriadis A, et al.
Oncogene . 2016 Oct; 36(13):1793-1803. PMID: 27694902
Aberrant Wnt signaling within breast cancer is associated with poor prognosis, but regulation of this pathway in breast tissue remains poorly understood and the consequences of immediate or long-term dysregulation...
3.
Barker N, Van Es J, Jaks V, Kasper M, Snippert H, Toftgard R, et al.
Cold Spring Harb Symp Quant Biol . 2009 May; 73:351-6. PMID: 19478326
The intestinal epithelium and the hair follicle represent examples of rapidly self-renewing tissue in adult mammals. We have recently identified a novel stem cell gene Lgr5 expressed in multiple adult...
4.
Fodde R, Kuipers J, Rosenberg C, Smits R, Kielman M, Gaspar C, et al.
Nat Cell Biol . 2001 Apr; 3(4):433-8. PMID: 11283620
Two forms of genetic instability have been described in colorectal cancer: microsatellite instability and chromosomal instability. Microsatellite instability results from mutations in mismatch repair genes; chromosomal instability is the hallmark...
5.
Van Es J, Giles R, Clevers H
Exp Cell Res . 2001 Mar; 264(1):126-34. PMID: 11237529
Inactivation of the tumor suppressor adenomatous polyposis coli (APC) protein is a critical early step in the development of familial and sporadic colon cancer. Close examination of the function of...
6.
Van Es J, Kirkpatrick C, van de Wetering M, Molenaar M, Miles A, Kuipers J, et al.
Curr Biol . 1999 Feb; 9(2):105-8. PMID: 10021369
The adenomatous polyposis coli (APC) tumour-suppressor protein controls the Wnt signalling pathway by forming a complex with glycogen synthase kinase 3beta (GSK-3beta), axin/conductin and betacatenin. Complex formation induces the rapid...
7.
Schutte M, Van Es J, Silberstein L, Logtenberg T
J Immunol . 1993 Dec; 151(11):6569-76. PMID: 7504024
The Ig VH regions of virtually all human pathogenic cold agglutinin (CA) anti-i/l autoantibodies are encoded by a single Ig VH gene segment, VH4.21, in conjunction with a highly variable...
8.
Van Es J, Raaphorst F, van Tol M, Meyling F, Logtenberg T
J Immunol . 1993 Jan; 150(1):161-8. PMID: 8417121
We have developed a mAb (JE-6) that recognizes an Id encoded by the most JH-proximal human VH gene segment (VH6) in or near germ-line configuration. This mAb was used to...
9.
Van Es J, Meyling F, Logtenberg T
Eur J Immunol . 1992 Oct; 22(10):2761-4. PMID: 1396981
Nucleotide sequence analysis of cDNA encoded by the single member of the human immunoglobulin VH6 gene family show that blood B cells in adults, but not in neonates, frequently express...
10.
Van Es J, Aanstoot H, Gmelig-Meyling F, Derksen R, Logtenberg T
J Immunol . 1992 Sep; 149(6):2234-40. PMID: 1517580
We report the Ig H and L chain V region sequences from the cDNAs encoding a monoclonal human IgG anti-cardiolipin/ssDNA autoantibody (R149) derived from a patient with active SLE. Comparison...