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M J Parmely

Explore the profile of M J Parmely including associated specialties, affiliations and a list of published articles. Areas
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Articles 33
Citations 246
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Recent Articles
1.
Parmely M, Wang F, Wright D
Infect Immun . 2001 Mar; 69(4):2621-9. PMID: 11254627
Oxidative stress occurs in animals challenged with bacterial endotoxin and can affect the expression of important host inflammatory genes. However, much less is known about the effects of oxidative stress...
2.
Xia D, Wang F, Parmely M
Biochem Pharmacol . 2000 Aug; 60(5):717-27. PMID: 10927031
Adenyl carbocyclic nucleosides have potent anti-inflammatory effects on a number of cell types. Notable in this regard is their ability to inhibit the production of tumor necrosis factor-alpha (TNF-alpha) by...
3.
Wang F, Wang L, Wright D, Parmely M
Infect Immun . 1999 Sep; 67(10):5409-16. PMID: 10496923
Endotoxemia is accompanied by significant changes in the reductive-oxidative (redox) balance of critical target organs. Redox stress has been shown to regulate the expression of proinflammatory genes that are induced...
4.
Leeson M, Rawitch A, Parmely M
J Interferon Cytokine Res . 1995 Jun; 15(6):557-67. PMID: 7553225
Mononuclear phagocytes produce proteinases that are thought to play a role in regulating the activity of cytokines. Activated macrophages secrete urokinase-type plasminogen activator (uPA), which mediates the formation of the...
5.
Hausmann E, Hao S, Pace J, Parmely M
Infect Immun . 1994 Sep; 62(9):3625-32. PMID: 8063378
Bacterial lipopolysaccharides (LPS) are potent inducers of macrophage activation, leading to the production of a number of proinflammatory mediators. Although several cytokines that prime macrophages for enhanced LPS-triggered responses have...
6.
Parmely M
J Biol Chem . 1994 Aug; 269(33):21353-7. PMID: 8063761
Urokinase-type plasminogen activator (uPA) is initially produced by cells as a single-chain precursor (pro-uPA), which can be cleaved by the serine protease plasmin to form the two-chain molecule uPA. This...
7.
Edwards 3rd C, Watts L, Parmely M, Linnik M, Long R, Borcherding D
J Leukoc Biol . 1994 Aug; 56(2):133-44. PMID: 8071590
The effects of the carbocyclic nucleoside MDL 201,112 and the purine nucleoside adenosine on the interferon-gamma (IFN-gamma)-induced priming of macrophages (m phi s) for the respiratory burst and major histocompatibility...
8.
Parmely M, Sterner K, Gale A, Zhou W
J Interferon Res . 1993 Dec; 13(6):397-406. PMID: 8151133
Urokinase-type plasminogen activator (uPA) converts the proenzyme plasminogen to plasmin and thereby contributes to processes like cell migration, tissue remodeling, and cytokine processing. We report here that uPA produced by...
9.
Parmely M, Zhou W, Edwards 3rd C, Borcherding D, SILVERSTEIN R, Morrison D
J Immunol . 1993 Jul; 151(1):389-96. PMID: 8326132
Adenosine (ADO) and its structurally related analogues are known to regulate the activities of immune and inflammatory cells, including a number of key functions of mononuclear phagocytes. In this study...
10.
Horvat R, Parmely M, Chandran B
J Infect Dis . 1993 Jun; 167(6):1274-80. PMID: 8388898
Human herpesvirus 6 (HHV-6) was recently isolated from the blood of immunosuppressed individuals and children with exanthem subitum. In this study, the effect of HHV-6 on the proliferative response of...