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M J Lewin

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Articles 109
Citations 896
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Recent Articles
1.
Lewin M
Drugs Today (Barc) . 2003 Sep; 35(10):743-52. PMID: 12973369
Hydrochloric acid (HCl) secretion into the gastric lumen is a specialized process driven primarily by H(+)/K(+)-ATPase or proton pump, a unique enzyme expressed in high quantities by the parietal cells....
2.
Goiot H, Attoub S, Kermorgant S, Laigneau J, Lardeux B, Lehy T, et al.
Gastroenterology . 2001 Dec; 121(6):1417-27. PMID: 11729121
Background & Aims: Leptin is a circulating hormone that communicates the peripheral nutritional status to the hypothalamus, which controls food intake, energy expenditure, and body weight. This study characterizes leptin...
3.
Buyse M, Berlioz F, Guilmeau S, Tsocas A, Voisin T, Peranzi G, et al.
J Clin Invest . 2001 Nov; 108(10):1483-94. PMID: 11714740
Dietary proteins are mostly absorbed as di- and tripeptides by the intestinal proton-dependent transporter PepT1. We have examined the effects of leptin on PepT1 function in rat jejunum and in...
4.
Kermorgant S, Dessirier V, Lewin M, Lehy T
Am J Physiol Gastrointest Liver Physiol . 2001 Sep; 281(4):G1068-80. PMID: 11557528
Hepatocyte growth factor (HGF) and its receptor, c-Met, are involved in cell transformation. To study their role in intestinal cell differentiation, we used Caco-2 colon cancer cells, which differentiate spontaneously...
5.
Buyse M, Ovesjo M, Goiot H, Guilmeau S, Peranzi G, Moizo L, et al.
Eur J Neurosci . 2001 Aug; 14(1):64-72. PMID: 11488950
Leptin, the product of the ob gene, plays a key role in the regulation of food intake via a cross-talk between hypothalamic leptin receptors and neuropeptides that affect feeding behaviour....
6.
Attoub S, Moizo L, Sobhani I, Laigneau J, Lewin M, Bado A
Life Sci . 2001 Jul; 69(4):469-78. PMID: 11459437
We investigated the peripheral effects of an H3-receptor agonist and an H3-receptor antagonist (R)alpha-methylhistamine (Ralpha-MeHA) and thioperamide, respectively, on basal feeding and the CCK8-induced inhibition of food intake in rat....
7.
Kermorgant S, Aparicio T, Dessirier V, Lewin M, Lehy T
Carcinogenesis . 2001 Jun; 22(7):1035-42. PMID: 11408346
Tumour progression to the metastatic phenotype is mainly dependent on tumour cell invasiveness. Cell migration is a crucial step in this process. Here we investigate the effect of hepatocyte growth...
8.
Lewin M, Bado A
Microsc Res Tech . 2001 May; 53(5):372-6. PMID: 11376498
The recent discovery of gastric leptin has initiated several investigations on the possible role of leptin in digestive physiology. The following clues are currently suggested: leptin might control meal size...
9.
Sadji Z, Le Romancer M, Lewin M, Reyl-Desmars F
Cell Signal . 2001 Jan; 12(11-12):745-50. PMID: 11152960
In this work, we used colon carcinoma cell-line HCT116 to study the involvement of the 86-kDa subunit (Ku86) of DNA-protein kinase (DNA-PK) in human tumoural cell proliferation. We transfected these...
10.
Hormi K, Cadiot G, Kermorgant S, Dessirier V, Le Romancer M, Lewin M, et al.
Growth Factors . 2000 Oct; 18(2):79-91. PMID: 11019780
Transforming growth factor-alpha (TGF-alpha) is overexpressed in colonic carcinomas and promotes mucosal wound healing. It may be implicated in chronic inflammatory bowel disease (IBD). We analyzed the expression of TGF-alpha...