M I Porn-Ares
Overview
Explore the profile of M I Porn-Ares including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
215
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Recent Articles
1.
Porn-Ares M, Ares M, Orrenius S
Toxicol In Vitro
. 2010 Jul;
12(5):539-43.
PMID: 20654437
Apoptotic cell death is characterized by cell shrinkage, chromatin condensation and fragmentation, formation of apoptotic bodies and phagocytosis (Kerr et al., 1972). At the molecular level, activation of a family...
2.
Chihab R, Porn-Ares M, Alvarado-Kristensson M, Andersson T
Cell Mol Life Sci
. 2003 Jun;
60(4):776-85.
PMID: 12785724
Sphingosine 1-phosphate (SPP) is associated with the regulation of apoptosis, although its role in neutrophil apoptosis remains poorly investigated. Here, we show that exogenous SPP antagonizes spontaneous and anti-Fas-induced apoptosis...
3.
Ares M, Porn-Ares M, Moses S, Thyberg J, Juntti-Berggren L, Berggren P, et al.
Atherosclerosis
. 2000 Nov;
153(1):23-35.
PMID: 11058697
In the present study, we characterize the early cytotoxic effects of 7beta-hydroxycholesterol, a major cytotoxin in oxidized LDL, in human aortic smooth muscle cells. Within a few minutes after addition,...
4.
Porn-Ares M, Samali A, Orrenius S
Cell Death Differ
. 1999 Jan;
5(12):1028-33.
PMID: 9894609
Calpain activity is thought to be essential for the execution of apoptotic cell death in certain experimental models. In the present study, the physiological inhibitor of calpain, calpastatin, was found...
5.
Ares M, Porn-Ares M, Thyberg J, Juntti-Berggren L, Berggren P, Diczfalusy U, et al.
J Lipid Res
. 1997 Nov;
38(10):2049-61.
PMID: 9374127
We have characterized the death of human aortic smooth muscle cells induced by 25-hydroxycholesterol, an oxidation product of cholesterol. Chromatin condensation characteristic of apoptosis was observed by enzymatic (TUNEL) staining...
6.
Porn-Ares M, Chow S, Slotte J, Orrenius S
Exp Cell Res
. 1997 Aug;
235(1):48-54.
PMID: 9281351
Apoptosis induced by ligation of either the tumor necrosis factor (TNF) p55 receptor or the Fas/APO-1/CD95 receptor has been suggested to require ceramide as a signaling molecule. Ceramide is formed...
7.
Hampton M, Vanags D, Porn-Ares M, Orrenius S
FEBS Lett
. 1996 Dec;
399(3):277-82.
PMID: 8985162
The appearance of phosphatidylserine (PS) on the outer surface of apoptotic cells is an important signal for their ingestion. In platelets, elevation of intracellular Ca2+ with thapsigargin can trigger large...
8.
Vanags D, Porn-Ares M, Coppola S, Burgess D, Orrenius S
J Biol Chem
. 1996 Dec;
271(49):31075-85.
PMID: 8940103
A detailed kinetic analysis of three extranuclear end points of apoptosis, phosphatidylserine exposure, alpha-fodrin degradation, and plasma membrane blebbing, was performed and compared with nuclear fragmentation and the activation of...