M I Koukourakis
Overview
Explore the profile of M I Koukourakis including associated specialties, affiliations and a list of published articles.
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Articles
102
Citations
2422
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0
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Recent Articles
1.
Anestopoulos I, Kyriakou S, Tragkola V, Paraskevaidis I, Tzika E, Mitsiogianni M, et al.
Pharmacol Ther
. 2022 Oct;
240:108301.
PMID: 36283453
Malignant melanoma is the most lethal type of skin cancer with high rates of mortality. Although current treatment options provide a short-clinical benefit, acquired-drug resistance highlights the low 5-year survival...
2.
Koukourakis M, Giatromanolaki A
Clin Transl Oncol
. 2020 May;
22(12):2196-2205.
PMID: 32445035
Radiotherapy is the treatment of choice for many cancer patients. Residual tumor leads to local recurrence after a period of an equilibrium created between proliferating, quiescent and dying cancer cells....
3.
Kalamida D, Giatromanolaki A, Koukourakis M
Methods Mol Biol
. 2019 Jan;
1880:555-560.
PMID: 30610722
A method is described for the immunostaining of human prostate cancer biopsies for the autophagic marker LC3 and the lysosomal protein LAMP2A. Using this combination we can provide some information...
4.
Koukourakis M, Giatromanolaki A, Bottini A, Cappelletti M, Zanotti L, Allevi G, et al.
Br J Cancer
. 2014 Apr;
110(9):2209-16.
PMID: 24722179
Background: Although Trastuzumab has improved survival of HER2+ breast cancer patients, resistance to the agent pre-exists or develops through the course of therapy. Here we show that a specific metabolism...
5.
Koukourakis M, Giatromanolaki A, Panteliadou M, Pouliliou S, Chondrou P, Mavropoulou S, et al.
Br J Cancer
. 2014 Apr;
110(9):2217-23.
PMID: 24714743
Background: Radiotherapy provides high-cure rates in prostate cancer. Despite its overall slow clinical growth, high proliferation rates documented in a subset of tumours relate to poor radiotherapy outcome. This study...
6.
Giatromanolaki A, Koukourakis M, Koutsopoulos A, Harris A, Gatter K, Sivridis E
Colorectal Dis
. 2013 Jan;
15(5):e223-30.
PMID: 23351172
Aim: The study investigated whether autophagic activity and hypoxia parallel the adenoma-carcinoma sequence. Method: The study comprised 120 tubular adenomas with high-grade dysplasia, including 22 with questionable evidence of invasion,...
7.
Giatromanolaki A, Koukourakis M, Sivridis E, Gatter K, Trarbach T, Folprecht G, et al.
Br J Cancer
. 2012 Aug;
107(7):1044-50.
PMID: 22910317
Background: Pharmacological inhibitors of vascular endothelial growth factor (VEGF) receptors, like vatalanib, have been tested in randomised trials (CONFIRM (Colorectal Oral Novel therapy For the Inhibition of Angiogenesis and Retarding...
8.
Koukourakis M, Giatromanolaki A, Tsakmaki V, Danielidis V, Sivridis E
Br J Cancer
. 2012 Feb;
106(5):846-53.
PMID: 22333601
Background: Cancer stem cells (CSCs) tend to repopulate malignant tumours during radiotherapy and, therefore, prolongation of the overall treatment time may result in radiotherapy failure. Thus, an estimate of the...
9.
Koukourakis M
Br J Radiol
. 2012 Feb;
85(1012):313-30.
PMID: 22294702
Exposure to ionising radiation results in mutagenesis and cell death, and the clinical manifestations depend on the dose and the involved body area. Reducing carcinogenesis in patients treated with radiotherapy,...
10.
Koukourakis M, Papadopoulou A, Kyrgias G
Hematol Oncol Stem Cell Ther
. 2011 Apr;
4(1):45-7.
PMID: 21460607
A patient with recurrent endometrial cancer with multiple abdominal and pelvic tumoral masses was treated with re-irradiation combined with liposomal doxorubicin and oxaliplatin. A multiple field conformal technique was used...