M H Malim
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Explore the profile of M H Malim including associated specialties, affiliations and a list of published articles.
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67
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5922
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Recent Articles
1.
Kim E, Schulz R, Swantek P, Kunstman K, Malim M, Wolinsky S
Gene Ther
. 2011 Jun;
19(3):347-53.
PMID: 21697957
The unique properties of oligonucleotide (and small interfering RNA)-modified gold nanoparticle conjugates make them promising intracellular gene regulation agents. We found that gold nanoparticles stably functionalized with covalently attached oligonucleotides...
2.
Dvorin J, Malim M
Curr Top Microbiol Immunol
. 2003 Aug;
281:179-208.
PMID: 12932078
After entry into the cytoplasm, many diverse viruses, including both RNA and DNA viruses, require import into the nucleus and access to the cellular nuclear machinery for productive replication to...
3.
Biochemical analyses of the interactions between human immunodeficiency virus type 1 Vpr and p6(Gag)
Jenkins Y, Pornillos O, Rich R, Myszka D, Sundquist W, Malim M
J Virol
. 2001 Oct;
75(21):10537-42.
PMID: 11581428
The nonstructural human immunodeficiency virus type 1 Vpr protein is packaged into progeny virions at significant levels (approximately 200 copies/virion). Genetic analyses have demonstrated that efficient Vpr packaging is dependent...
4.
Jenkins Y, Sanchez P, Meyer B, Malim M
J Virol
. 2001 Aug;
75(17):8348-52.
PMID: 11483780
The human immunodeficiency virus type 1 Vpr protein is both packaged into virions and efficiently localized to the nucleus. In this report, we show that a significant fraction of Vpr...
5.
Dvorin J, Fouchier R, Jenkins Y, Meyer B, Wu L, Emerman M, et al.
Mol Cell
. 2001 Jun;
7(5):1025-35.
PMID: 11389849
HIV-1 is able to infect nondividing cells productively in part because the postentry viral nucleoprotein complexes are actively imported into the nucleus. In this manuscript, we identify a novel nuclear...
6.
MEANS R, Matthews T, Hoxie J, Malim M, Kodama T, Desrosiers R
J Virol
. 2001 Mar;
75(8):3903-15.
PMID: 11264379
To better define the effects of sequence variation and tropism on the ability of the simian immunodeficiency virus SIVmac V3 loop to act as a target of antibody-mediated neutralization, a...
7.
8.
Alexander L, Weiskopf E, Greenough T, Gaddis N, Auerbach M, Malim M, et al.
J Virol
. 2001 Feb;
74(9):4361-76.
PMID: 10756051
Factors accounting for long-term nonprogression may include infection with an attenuated strain of human immunodeficiency virus type 1 (HIV-1), genetic polymorphisms in the host, and virus-specific immune responses. In this...
9.
Fultz P, Vance P, Endres M, Tao B, Dvorin J, Davis I, et al.
J Virol
. 2000 Dec;
75(1):278-91.
PMID: 11119598
Attenuated simian immunodeficiency viruses (SIVs) have been described that produce low levels of plasma virion RNA and exhibit a reduced capacity to cause disease. These viruses are particularly useful in...
10.
ODoherty U, Swiggard W, Malim M
J Virol
. 2000 Oct;
74(21):10074-80.
PMID: 11024136
The study of early events in the human immunodeficiency virus type 1 (HIV-1) life cycle can be limited by the relatively low numbers of cells that can be infected synchronously...