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M G Elgort

Explore the profile of M G Elgort including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 120
Followers 0
Related Specialties
Biochemistry
Molecular Biology
Parasitology
Top 10 Co-Authors
E A Allegretto
A Zou
D A Campbell
R A HEYMAN
M F Boehm
S Wong
J Lom
L Mere
D A Maslov
H Peckova
Published In
Mol Biochem Parasitol
J Biol Chem
Mol Endocrinol
EMBO J
Chem Biol
Affiliations
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Recent Articles
1.
Novel nonsecosteroidal vitamin D mimics exert VDR-modulating activities with less calcium mobilization than 1,25-dihydroxyvitamin D3
Boehm M, Fitzgerald P, Zou A, Elgort M, Bischoff E, Mere L, et al.
Chem Biol . 1999 May; 6(5):265-75. PMID: 10322128
Background: The secosteroid 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) acts through the vitamin D receptor (VDR) to elicit many activities that make it a promising drug candidate for the treatment of a number...
2.
Retinoid X receptor (RXR) ligands activate the human 25-hydroxyvitamin D3-24-hydroxylase promoter via RXR heterodimer binding to two vitamin D-responsive elements and elicit additive effects with 1,25-dihydroxyvitamin D3
Zou A, Elgort M, Allegretto E
J Biol Chem . 1997 Jul; 272(30):19027-34. PMID: 9228086
We have previously shown that RNA levels of kidney 25-hydroxyvitamin D3-24-hydroxylase (24(OH)ase), a key metabolic enzyme for 1,25-dihydroxyvitamin D3 (1,25(OH)2D3), is up-regulated by retinoids in mice within hours. Deletion analysis...
3.
Estrogen and estrogen receptor antagonists stimulate transcription from the human retinoic acid receptor-alpha 1 promoter via a novel sequence
Elgort M, Zou A, Marschke K, Allegretto E
Mol Endocrinol . 1996 May; 10(5):477-87. PMID: 8732679
We and others previously reported that up-regulation of retinoic acid receptor-alpha (RAR alpha) RNA and protein levels is elicited by estrogen in human breast cancer cells. We set out to...
4.
A conserved upstream element is essential for transcription of the Leishmania tarentolae mini-exon gene
Saito R, Elgort M, Campbell D
EMBO J . 1994 Nov; 13(22):5460-9. PMID: 7957112
We demonstrate that the mini-exon genes of Leishmania tarentolae are individually transcribed by an enzyme pharmacologically identified as RNA polymerase II. To study transcription in these ancient eukaryotes, a stable...
5.
Transactivation properties of retinoic acid and retinoid X receptors in mammalian cells and yeast. Correlation with hormone binding and effects of metabolism
Allegretto E, McClurg M, Lazarchik S, Clemm D, Kerner S, Elgort M, et al.
J Biol Chem . 1993 Dec; 268(35):26625-33. PMID: 8253793
The binding affinities of 9-cis-retinoic acid (9-cis-RA) and all-trans-retinoic acid (t-RA) for retinoic acid receptors (RAR) alpha, beta, and gamma and for retinoid X receptors (RXR) alpha, beta, and gamma...
6.
Organization of mini-exon and 5S rRNA genes in the kinetoplastid Trypanoplasma borreli
Maslov D, Elgort M, Wong S, Peckova H, Lom J, Simpson L, et al.
Mol Biochem Parasitol . 1993 Sep; 61(1):127-35. PMID: 8259125
Mini-exon gene repeats from Trypanoplasma borreli, which belongs to the Cryptobiidae family of the Bodonina suborder of the Kinetoplastida, were isolated by PCR amplification and cloning. The presence of kinetoplastid-like...
7.
Allelic polymorphism of the Trypanosoma brucei polyubiquitin gene
Wong S, Elgort M, Gottesdiener K, Campbell D
Mol Biochem Parasitol . 1992 Oct; 55(1-2):187-95. PMID: 1331786
We have characterized a second T. brucei polyubiquitin gene (UbB) that is highly similar in the coding and flanking regions to a previously described T. brucei polyubiquitin gene (UbA). However,...