M F Hirshman
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Explore the profile of M F Hirshman including associated specialties, affiliations and a list of published articles.
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50
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4265
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Recent Articles
21.
Markuns J, Napoli R, Hirshman M, Davalli A, Cheatham B, Goodyear L
Endocrinology
. 1999 Jan;
140(1):106-11.
PMID: 9886813
Streptozocin-induced diabetes is associated with alterations in insulin signaling in rat skeletal muscle, including increased insulin receptor substrate-1 phosphorylation and phosphotidylinositol 3-kinase activity. In the current study, we determined the...
22.
Napoli R, Gibson L, Hirshman M, Boppart M, Dufresne S, Horton E, et al.
Diabetes
. 1998 Sep;
47(10):1549-54.
PMID: 9753291
Little is known about the regulation of the mitogen-activated protein (MAP) kinase signaling cascades by hormonal stimulation in vivo. The extracellular signal-regulated kinase (ERK) and the c-jun kinase (JNK) are...
23.
Hayashi T, Hirshman M, Kurth E, Winder W, Goodyear L
Diabetes
. 1998 Aug;
47(8):1369-73.
PMID: 9703344
The intracellular signaling proteins that lead to exercise-stimulated glucose transport in skeletal muscle have not been identified, although it is clear that there are separate signaling mechanisms for exercise- and...
24.
De Souza C, Hirshman M, Horton E
Diabetes
. 1997 Aug;
46(8):1257-63.
PMID: 9231648
Administration of the murine-selective beta3 adrenoceptor agonist CL-316,243 corrects obesity and elevated blood glucose in diabetic rodents. This antiobesity effect is attributed to an increase in the thermogenic activity of...
25.
Davalli A, Napoli R, Weitgasser R, Capotorto J, Hirshman M, Finegood D, et al.
J Endocrinol
. 1996 Aug;
150(2):255-63.
PMID: 8869592
Skeletal muscle GLUT-4 content is decreased in streptozotocin (STZ)-diabetic rats. This decrease is associated with impairment in glucose transport across the plasma membrane. In this study we investigated whether islet...
26.
Goodyear L, Hirshman M, Napoli R, Calles J, Markuns J, Ljungqvist O, et al.
Diabetes
. 1996 Aug;
45(8):1051-6.
PMID: 8690151
In humans, ingestion of carbohydrates causes an increase in blood glucose concentration, pancreatic insulin release, and increased glucose disposal into skeletal muscle. The underlying molecular mechanism for the increase in...
27.
Napoli R, Cittadini A, Chow J, Hirshman M, Smith R, Douglas P, et al.
Biochem J
. 1996 May;
315 ( Pt 3):959-63.
PMID: 8645183
Whether skeletal muscle glucose transport system is impaired in the basal, post-prandial state during chronic growth hormone treatment is unknown. The current study was designed to determine whether 4 weeks...
28.
Napoli R, Davalli A, Hirshman M, Weitgasser R, Weir G, Horton E
J Clin Invest
. 1996 Mar;
97(6):1389-97.
PMID: 8617870
Chronic insulin therapy improves but does not restore impaired insulin-mediated muscle glucose uptake in human diabetes or muscle glucose uptake, transport, and transporter translocation in streptozocin diabetic rats. To determine...
29.
Calles-Escandon J, Sweet L, Ljungqvist O, Hirshman M
Life Sci
. 1996 Jan;
58(1):19-28.
PMID: 8628107
Muscle tissue (1.1 +/- 0.1 grams) was obtained from seven healthy individuals (3 males, 4 females) using an open incision approach before and after ingestion of either 75 grams of...
30.
Sherman L, Hirshman M, Cormont M, Le Marchand-Brustel Y, Goodyear L
Endocrinology
. 1996 Jan;
137(1):266-73.
PMID: 8536622
Insulin and exercise cause the translocation of GLUT4 from an intracellular location to the plasma membrane in skeletal muscle. The purpose of this study was to determine if Rab4, a...