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M E Lancaster

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Citations 233
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Recent Articles
1.
Persky A, Ng C, Song M, Lancaster M, Balderson D, Paulik M, et al.
Int J Clin Pharmacol Ther . 2004 Sep; 42(8):442-8. PMID: 15366324
Objective: With an increase in the incidence of obesity, tremendous effort has been devoted to the development of weight loss agents and the prospective surrogate markers of both a product's...
2.
Lenhard J, Lancaster M, Paulik M, Weiel J, Binz J, Sundseth S, et al.
Diabetologia . 1999 May; 42(5):545-54. PMID: 10333046
Aims/hypothesis: Although retinoid X receptor (RXR) and peroxisome proliferator activated receptor-gamma (PPARgamma) agonists have antidiabetic effects in hyperinsulinaemic animals, little information exists on their effects after pancreatic beta-cell failure. Thus,...
3.
Paulik M, Buckholz R, Lancaster M, Dallas W, Hull-Ryde E, Weiel J, et al.
Pharm Res . 1998 Jul; 15(6):944-9. PMID: 9647363
Purpose: Although the effects of thermogenic agents in cell culture can be measured by direct microcalorimetry, only a few samples can be analyzed over several hours. In this report, we...
4.
Roe M, Worley 3rd J, Mittal A, Kuznetsov A, Dasgupta S, Mertz R, et al.
J Biol Chem . 1996 Dec; 271(50):32241-6. PMID: 8943282
Voltage-dependent delayed rectifier K+ channels regulate aspects of both stimulus-secretion and excitation-contraction coupling, but assigning specific roles to these channels has proved problematic. Using transgenically derived insulinoma cells (betaTC3-neo) and...
5.
Roe M, Spencer B, Lancaster M, Mertz R, Worley 3rd J, Dukes I
Diabetologia . 1995 Jul; 38(7):876-9. PMID: 7556996
No abstract available.
6.
Philipson L, Rosenberg M, Kuznetsov A, Lancaster M, Worley 3rd J, Roe M, et al.
J Biol Chem . 1994 Nov; 269(45):27787-90. PMID: 7961701
Glucose stimulation of pancreatic beta-cell insulin secretion is closely coupled to alterations in ion channel conductances and intracellular Ca2+ ([Ca2+]i). To further examine this relationship after augmentation of voltage-dependent K+...
7.
Roe M, Philipson L, Frangakis C, Kuznetsov A, Mertz R, Lancaster M, et al.
J Biol Chem . 1994 Jul; 269(28):18279-82. PMID: 8034570
Non-insulin-dependent diabetes mellitus (NIDDM) is a metabolic disease associated with abnormal insulin secretion, the underlying mechanisms of which are unknown. Glucose-dependent signal transduction pathways were investigated in pancreatic islets derived...
8.
Roe M, Mertz R, Lancaster M, Worley 3rd J, Dukes I
Am J Physiol . 1994 Jun; 266(6 Pt 1):E852-62. PMID: 8023914
Stimulation of pancreatic islets of Langerhans with glucose results in changes in intracellular Ca2+ concentration ([Ca2+]i). With the use of mouse islets loaded with fura 2, the earliest glucose-induced alteration...
9.
Roe M, Lancaster M, Mertz R, Worley 3rd J, Dukes I
J Biol Chem . 1993 May; 268(14):9953-6. PMID: 8387528
Glucose-activated beta-cell insulin secretion depends upon elevation of intracellular calcium concentration, [Ca2+]i, which is thought to arise from Ca2+ influx through voltage-dependent calcium channels. Using fura-2-loaded mouse islets, we demonstrate,...
10.
Gadsby J, Lancaster M
Biol Reprod . 1989 Feb; 40(2):239-49. PMID: 2720025
The rabbit fetal placenta plays an important physiological role in luteal maintenance in pregnancy, probably via the secretion of an unidentified placental "luteotropin." The objective of these studies was to...