M E Furth
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Explore the profile of M E Furth including associated specialties, affiliations and a list of published articles.
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33
Citations
1458
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Recent Articles
11.
MEYERS M, Shen W, Spengler B, Ciccarone V, OBrien J, Donner D, et al.
J Cell Biochem
. 1988 Oct;
38(2):87-97.
PMID: 2464605
Multidrug-resistant human neuroblastoma cell lines obtained by selection with vincristine or actinomycin D from two independent clonal lines, SH-SY5Y and MC-IXC, have 3- to 30-fold more cell surface epidermal growth...
12.
Souyri M, Koehne C, ODonnell P, Aldrich T, Furth M, Fleissner E
Virology
. 1987 May;
158(1):69-78.
PMID: 3576974
We have introduced a genomic DNA clone of a mutated human N-ras gene from a T-cell leukemia cell line into a retroviral vector equipped with a neo resistance gene and...
13.
Shen W, Aldrich T, Venta-Perez G, Franza Jr B, Furth M
Oncogene
. 1987 May;
1(2):157-65.
PMID: 3325880
The expression of normal and mutant ras genes in human acute leukemias was assessed by the direct analysis of p21ras polypeptides, using immunoprecipitation with monoclonal antibodies. High-resolution two-dimensional gel electrophoresis...
14.
Bizub D, Heimer E, Felix A, Chizzonite R, Wood A, Skalka A, et al.
Oncogene
. 1987 May;
1(2):131-42.
PMID: 2449645
Antisera were prepared in mice, rats and rabbits by immunization with peptides corresponding to regions of highest variability, located near the C-termini of four ras proteins. Two of these, H-ras...
15.
Furth M, Aldrich T, Cordon-Cardo C
Oncogene
. 1987 Mar;
1(1):47-58.
PMID: 3125507
The expression of ras proto-oncogenes in normal human tissues was studied by immunohistochemical staining and by immunoblotting using monoclonal antibodies. We detected p21ras protein in almost every fetal and adult...
16.
Ballester R, Furth M, Rosen O
J Biol Chem
. 1987 Feb;
262(6):2688-95.
PMID: 3546293
The effect of phorbol 12-myristate 13-acetate on the phosphorylation of the ras p21 protein was studied by metabolically labeling cultured cells with [32P]orthophosphate and using a monoclonal antibody to immunoprecipitate...
17.
Swanson M, Elste A, Greenberg S, Schwartz J, Aldrich T, Furth M
J Cell Biol
. 1986 Aug;
103(2):485-92.
PMID: 3525576
We have cloned a DNA fragment from the marine mollusc Aplysia californica, which contains sequences homologous to mammalian ras genes, by screening a genomic library with a viral Ha-ras oncogene...
18.
Andreeff M, Slater D, Bressler J, Furth M
Blood
. 1986 Mar;
67(3):676-81.
PMID: 3511984
Human hematopoietic malignancies provide an excellent model for the study of the activity of cellular oncogenes in a context of known defects in cell proliferation and differentiation. A flow cytometric...
19.
Albino A, Le Strange R, Oliff A, Furth M, Old L
Nature
. 1984 Mar;
308(5954):69-72.
PMID: 6700714
Variability in the phenotype of cells comprising individual tumours is a striking feature of animal and human cancer and is generally referred to as tumour heterogeneity. Studies of clonally derived...
20.
Mouse cells contain two distinct ras gene mRNA species that can be translated into a p21 onc protein
Ellis R, Defeo D, Furth M, Scolnick E
Mol Cell Biol
. 1982 Nov;
2(11):1339-45.
PMID: 6131379
The Kirsten (Ki) and Harvey (Ha) strains of murine sarcoma virus encode a 21,000-dalton protein (p21 ras) which is the product of the transforming gene of these viruses. Normal cells...