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E M Scolnick

Explore the profile of E M Scolnick including associated specialties, affiliations and a list of published articles. Areas
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Articles 204
Citations 8220
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Recent Articles
1.
Song J, Bergen S, Di Florio A, Karlsson R, Charney A, Ruderfer D, et al.
Mol Psychiatry . 2017 Feb; 22(8):1223. PMID: 28194006
This corrects the article DOI: 10.1038/mp.2015.165.
2.
Kim M, Biag J, Fass D, Lewis M, Zhang Q, Fleishman M, et al.
Mol Psychiatry . 2016 Jul; 22(3):417-429. PMID: 27457813
Although the pathogenesis of schizophrenia (SCZ) is proposed to involve alterations of neural circuits via synaptic dysfunction, the underlying molecular mechanisms remain poorly understood. Recent exome sequencing studies of SCZ...
3.
Song J, Bergen S, Di Florio A, Karlsson R, Charney A, Ruderfer D, et al.
Mol Psychiatry . 2015 Oct; 21(9):1290-7. PMID: 26503763
Lithium is the mainstay prophylactic treatment for bipolar disorder (BD), but treatment response varies considerably across individuals. Patients who respond well to lithium treatment might represent a relatively homogeneous subtype...
4.
Rees E, Kirov G, Walters J, Richards A, Howrigan D, Kavanagh D, et al.
Transl Psychiatry . 2015 Jul; 5:e607. PMID: 26196440
Genetic associations involving both rare and common alleles have been reported for schizophrenia but there have been no systematic scans for rare recessive genotypes using fully phased trio data. Here,...
5.
Bergen S, ODushlaine C, Ripke S, Lee P, Ruderfer D, Akterin S, et al.
Mol Psychiatry . 2012 Jun; 17(9):880-6. PMID: 22688191
Schizophrenia (SCZ) and bipolar disorder (BD) are highly heritable psychiatric disorders with overlapping susceptibility loci and symptomatology. We conducted a genome-wide association study (GWAS) of these disorders in a large...
6.
Liu Y, Blackwood D, Caesar S, de Geus E, Farmer A, Ferreira M, et al.
Mol Psychiatry . 2010 Mar; 16(1):2-4. PMID: 20351715
No abstract available.
7.
Sklar P, Smoller J, Fan J, Ferreira M, Perlis R, Chambert K, et al.
Mol Psychiatry . 2008 Mar; 13(6):558-69. PMID: 18317468
We performed a genome-wide association scan in 1461 patients with bipolar (BP) 1 disorder, 2008 controls drawn from the Systematic Treatment Enhancement Program for Bipolar Disorder and the University College...
8.
Insel T, Scolnick E
Mol Psychiatry . 2005 Dec; 11(1):11-7. PMID: 16355250
Mental disorders cause more disability than any other class of medical illness in Americans between ages 15 and 44 years. The suicide rate is higher than the annual mortality from...
9.
Shoop W, Xiong Y, Wiltsie J, Woods A, Guo J, Pivnichny J, et al.
Proc Natl Acad Sci U S A . 2005 May; 102(22):7958-63. PMID: 15911756
The primary virulence factor of Bacillus anthracis is a secreted zinc-dependent metalloprotease toxin known as lethal factor (LF) that is lethal to the host through disruption of signaling pathways, cell...
10.
Scolnick E, Slater E, Williams G
Adv Protein Chem . 2001 May; 56:1-12. PMID: 11329850
No abstract available.