M David Stewart
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Explore the profile of M David Stewart including associated specialties, affiliations and a list of published articles.
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30
Citations
614
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Recent Articles
1.
Qasim H, Rajaei M, Xu Y, Reyes-Alcaraz A, Abdelnasser H, Stewart M, et al.
Circ Res
. 2024 Mar;
134(8):1006-1022.
PMID: 38506047
Background: In heart failure, signaling downstream the β2-adrenergic receptor is critical. Sympathetic stimulation of β2-adrenergic receptor alters cAMP (cyclic adenosine 3',5'-monophosphate) and triggers PKA (protein kinase A)-dependent phosphorylation of proteins...
2.
Stewart C, Stewart M, Wang Y, Mullen R, Kircher B, Liang R, et al.
Endocrinology
. 2022 Feb;
163(3).
PMID: 35134138
Female mice homozygous for an engineered Gnrhr E90K mutation have reduced gonadotropin-releasing hormone signaling, leading to infertility. Their ovaries have numerous antral follicles but no corpora lutea, indicating a block...
3.
Liang R, Shen X, Wang F, Wang X, DesJarlais A, Syed A, et al.
J Cachexia Sarcopenia Muscle
. 2021 Oct;
12(6):2174-2186.
PMID: 34704401
Background: Skeletal muscle atrophy is a debilitating complication of many chronic diseases, disuse conditions, and ageing. Genome-wide gene expression analyses have identified that elevated levels of microRNAs encoded by the...
4.
Roberston M, Raghunathan S, Potaman V, Zhang F, Stewart M, McConnell B, et al.
FASEB J
. 2020 Jan;
34(1):555-570.
PMID: 31914652
Muscle wasting, or muscle atrophy, can occur with age, injury, and disease; it affects the quality of life and complicates treatment. Insulin-like growth factor 1 (IGF1) is a key positive...
5.
Raghunathan S, Reynolds C, Schwartz R, Stewart M, McConnell B
Fundam Clin Pharmacol
. 2018 Jul;
33(1):25-30.
PMID: 29959870
Inbred mouse strains are the most widely used mammalian model organism in biomedical research owing to ease of genetic manipulation and short lifespan; however, each inbred strain possesses a unique...
6.
Nagandla H, Stewart M
Methods Mol Biol
. 2017 Aug;
1668:167-176.
PMID: 28842909
Mammalian myogenesis occurs in two distinct phases, primary and secondary, which are temporally separated. The primary wave occurs shortly after somitogenesis producing embryonic myofibers. The secondary wave occurs after somitogenesis...
7.
Valenzuela N, Soibam B, Li L, Wang J, Byers L, Liu Y, et al.
J Cell Sci
. 2017 Jun;
130(15):2551-2563.
PMID: 28600325
Nucleosome assembly proceeds through DNA replication-coupled or replication-independent mechanisms. For skeletal myocytes, whose nuclei have permanently exited the cell cycle, replication-independent assembly is the only mode available for chromatin remodeling....
8.
Fu S, Cheng J, Wei C, Yang L, Xiao X, Zhang D, et al.
Oncotarget
. 2017 Apr;
8(27):43866-43877.
PMID: 28410206
Cancer is genetically heterogeneous regarding to molecular genetic characteristics and pathogenic pathways. A wide spectrum of biomarkers, including DNA markers, is used in determining genomic instability, molecular subtype determination and...
9.
Liu Y, Chen L, Diaz Diaz A, Benham A, Xu X, Wijaya C, et al.
Sci Rep
. 2016 Aug;
6:31457.
PMID: 27538477
Mesp1 directs multipotential cardiovascular cell fates, even though it's transiently induced prior to the appearance of the cardiac progenitor program. Tracing Mesp1-expressing cells and their progeny allows isolation and characterization...
10.
Stewart M, Lopez S, Nagandla H, Soibam B, Benham A, Nguyen J, et al.
Dis Model Mech
. 2016 Mar;
9(3):347-59.
PMID: 26935107
The Smyd1 gene encodes a lysine methyltransferase specifically expressed in striated muscle. Because Smyd1-null mouse embryos die from heart malformation prior to formation of skeletal muscle, we developed a Smyd1...