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M C Gray

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Articles 27
Citations 713
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Recent Articles
1.
Page K, Martinson L, Hastings R, Fernandez-Garcia D, Gleason K, Gray M, et al.
Ann Oncol . 2021 May; 32(8):1057-1060. PMID: 33932505
No abstract available.
2.
Gray M, Gowrie Mohan S, Suxena A, Selvakumar S
Anaesth Intensive Care . 2014 Mar; 42(2):266-7. PMID: 24580398
No abstract available.
3.
Lee S, Gray M, Zu K, Hewlett E
Arch Biochem Biophys . 2005 May; 438(1):80-7. PMID: 15878155
Adenylate cyclase (AC) toxin from Bordetella pertussis inserts into eukaryotic cells, producing intracellular cAMP, as well as hemolysis and cytotoxicity. Concentration dependence of hemolysis suggests oligomers as the functional unit...
4.
Gray M, Donato G, Jones F, Kim T, Hewlett E
Mol Microbiol . 2004 Sep; 53(6):1709-19. PMID: 15341649
Adenylate cyclase (AC) toxin is present on the surface of Bordetella pertussis organisms and their addition to eukaryotic cells results in increases in intracellular cAMP. To test the hypothesis that...
5.
Rhodes C, Gray M, Watson J, Muratore T, Kim S, Hewlett E, et al.
Arch Biochem Biophys . 2001 Nov; 395(2):169-76. PMID: 11697853
Adenylyl cyclase toxin of Bordetella pertussis has been shown by several investigators to require Ca(2+) for its actions on target cells, but little is known about the nature and specificity...
6.
Gray M, Lee S, Gray L, Zaretzky F, Otero A, Szabo G, et al.
J Bacteriol . 2001 Sep; 183(20):5904-10. PMID: 11566989
Bordetella pertussis adenylate cyclase (AC) toxin belongs to the RTX family of toxins but is the only member with a known catalytic domain. The principal pathophysiologic function of AC toxin...
7.
Hewlett E, Kim K, Lee S, Gray M
Int J Med Microbiol . 2000 Dec; 290(4-5):333-5. PMID: 11111907
Adenylate cyclase (AC) toxin produced by Bordella pertussis and other Bordella species is a virulence factor and protective antigen with novel properties and activities, which make it attractive as a...
8.
Weingart C, Hewlett E, Gray M, Weiss A
Infect Immun . 2000 Nov; 68(12):7152-5. PMID: 11083845
A previous study showed that opsonization with human immune serum could either promote or antagonize phagocytosis of Bordetella pertussis by human neutrophils depending on whether the bacteria expressed adenylate cyclase...
9.
Gray M, Ross W, Kim K, Hewlett E
Infect Immun . 1999 Aug; 67(9):4393-9. PMID: 10456879
Adenylate cyclase (AC) toxin from Bordetella pertussis intoxicates eukaryotic cells by increasing intracellular cyclic AMP (cAMP) levels. In addition, insertion of AC toxin into the plasma membrane causes efflux of...
10.
Lee S, Gray M, Guo L, Sebo P, Hewlett E
Infect Immun . 1999 May; 67(5):2090-5. PMID: 10225859
Adenylate cyclase (AC) toxin from Bordetella pertussis is a 177-kDa repeats-in-toxin (RTX) family protein that consists of four principal domains; the catalytic domain, the hydrophobic domain, the glycine/aspartate-rich repeat domain,...