V M Gordon
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Explore the profile of V M Gordon including associated specialties, affiliations and a list of published articles.
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21
Citations
1222
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Recent Articles
1.
Gordon V, Culp M, Wolinetz C
Clin Transl Sci
. 2017 Jan;
10(3):130-132.
PMID: 28083989
No abstract available.
2.
Gordon V, Opfer-Gehrking T, Novak V, Low P
Clin Auton Res
. 2000 Apr;
10(1):29-33.
PMID: 10750641
A variety of approaches have been used to alleviate symptoms in postural tachycardia syndrome (POTS). Drugs reported to be of benefit include midodrine, propranolol, clonidine, and phenobarbital. Other measures used...
3.
Gordon V, Nelson K, Buckley J, Stevens V, Tweten R, Elwood P, et al.
J Biol Chem
. 1999 Sep;
274(38):27274-80.
PMID: 10480947
The alpha toxin produced by Clostridium septicum is a channel-forming protein that is an important contributor to the virulence of the organism. Chinese hamster ovary (CHO) cells are sensitive to...
4.
Duesbery N, Webb C, Leppla S, Gordon V, Klimpel K, Copeland T, et al.
Science
. 1998 May;
280(5364):734-7.
PMID: 9563949
Anthrax lethal toxin, produced by the bacterium Bacillus anthracis, is the major cause of death in animals infected with anthrax. One component of this toxin, lethal factor (LF), is suspected...
5.
Gordon V, Benz R, Fujii K, Leppla S, Tweten R
Infect Immun
. 1997 Oct;
65(10):4130-4.
PMID: 9317018
Clostridium septicum alpha-toxin is secreted as an inactive 46,450-Da protoxin. The protoxin is activated by proteolytic cleavage near the C terminus, which eventually causes the release of a 45-amino-acid fragment....
6.
Gordon V, Rehemtulla A, Leppla S
Infect Immun
. 1997 Aug;
65(8):3370-5.
PMID: 9234799
Several bacterial protein toxins require activation by eukaryotic proteases. Previous studies have shown that anthrax toxin protective antigen (PA), Pseudomonas exotoxin A (PE), and diphtheria toxin (DT) are cleaved by...
7.
Gu M, Gordon V, Fitzgerald D, Leppla S
Infect Immun
. 1996 Feb;
64(2):524-7.
PMID: 8550202
Pseudomonas exotoxin A (PE) binds and enters mammalian cells via the alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein (LRP). The toxin then requires proteolytic cleavage to generate an enzymatically active...
8.
Gordon V, Bonkovsky F
J Clin Ethics
. 1996 Jan;
7(4):349-54; discussion 362-4.
PMID: 9029336
No abstract available.
9.
Bosworth B, Samuel J, Moon H, OBrien A, Gordon V, Whipp S
Infect Immun
. 1996 Jan;
64(1):55-60.
PMID: 8557374
Escherichia coli strains producing Shiga-like toxin II variant (SLT-IIe, formerly called SLT-IIv) cause edema disease in weaned pigs. Vaccination of pigs with a genetically modified form of Shiga-like toxin IIe,...
10.
Friedman T, Gordon V, Leppla S, Klimpel K, Birch N, Loh Y
Arch Biochem Biophys
. 1995 Jan;
316(1):5-13.
PMID: 7840657
Protective antigen (PA), an 83-kDa protein produced by Bacillus anthracis, requires proteolytic activation at a tetrabasic site (RKKR167) before it can combine with either edema factor or lethal factor on...