M C Dinauer
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Explore the profile of M C Dinauer including associated specialties, affiliations and a list of published articles.
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76
Citations
3458
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Recent Articles
1.
Sadat M, Dirscherl S, Sastry L, Dantzer J, Pech N, Griffin S, et al.
Gene Ther
. 2009 Aug;
16(12):1452-64.
PMID: 19657370
X-linked chronic granulomatous disease (X-CGD) is an inherited immunodeficiency with absent phagocyte NADPH-oxidase activity caused by defects in the gene-encoding gp91(phox). Here, we evaluated strategies for less intensive conditioning for...
2.
Automated analysis of viral integration sites in gene therapy research using the SeqMap web resource
Peters B, Dirscherl S, Dantzer J, Nowacki J, Cross S, Li X, et al.
Gene Ther
. 2008 Jun;
15(18):1294-8.
PMID: 18580967
Research in gene therapy involving genome-integrating vectors now often includes analysis of vector integration sites across the genome using methods such as ligation-mediated PCR (LM-PCR) or linear amplification-mediated PCR (LAM-PCR)....
3.
Aratani Y, Kura F, Watanabe H, Akagawa H, Takano Y, Suzuki K, et al.
Med Mycol
. 2003 Jan;
40(6):557-63.
PMID: 12521119
Generation of oxidative products by phagocytic cells is known to be an important host defense mechanism directed toward killing of invading microorganisms. The importance of two major oxidant-producing enzymes, myeloperoxidase...
4.
Potter S, Sanni L, Simasathiansophon S, Dinauer M, Hunt N
Redox Rep
. 2001 Aug;
6(3):200-3.
PMID: 11523600
No abstract available.
5.
DeCoursey T, Cherny V, Morgan D, Katz B, Dinauer M
J Biol Chem
. 2001 Jul;
276(39):36063-6.
PMID: 11477065
During the "respiratory burst," the NADPH oxidase complex of phagocytes produces reactive oxygen species that kill bacteria and other invaders (Babior, B. M. (1999) Blood 93, 1464-1476). Electron efflux through...
6.
DeLeo F, Epstein R, LeRoy B, Nauseef W, Dinauer M
J Biol Chem
. 2001 Jun;
276(33):31105-12.
PMID: 11413138
The phagocyte NADPH-dependent oxidase generates superoxide (O(2)) by reducing molecular oxygen through flavocytochrome b(558) (flavocytochrome b), a heterodimeric oxidoreductase composed of gp91(phox) and p22(phox) subunits. Although each flavocytochrome b molecule...
7.
Dinauer M, GIFFORD M, Pech N, Li L, Emshwiller P
Blood
. 2001 Jun;
97(12):3738-45.
PMID: 11389011
Chronic granulomatous disease (CGD) is an inherited immunodeficiency in which the absence of the phagocyte superoxide-generating nicotinamide adenine dinucleotide phosphate (NADPH) oxidase results in recurrent bacterial and fungal infections. A...
8.
Yamauchi A, Yu L, Potgens A, Kuribayashi F, Nunoi H, Kanegasaki S, et al.
Microbiol Immunol
. 2001 May;
45(3):249-57.
PMID: 11345535
Flavocytochrome b558 is the membrane component of the phagocyte NADPH oxidase, and is a heterodimer composed of gp91phox and p22phox subunits. Human flavocytochrome b558 is recognized by monoclonal antibody 7D5...
9.
Ozaki M, Deshpande S, Angkeow P, Bellan J, Lowenstein C, Dinauer M, et al.
Transplant Proc
. 2001 Mar;
33(1-2):863-4.
PMID: 11267105
No abstract available.
10.
Kim C, Dinauer M
J Immunol
. 2001 Jan;
166(2):1223-32.
PMID: 11145705
Rac2 is a hematopoietic-specific Rho family GTPase implicated as an important constituent of the NADPH oxidase complex and shares 92% amino acid identity with the ubiquitously expressed Rac1. In bone...