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M Aizawa-Abe

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Citations 513
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Recent Articles
1.
Yamamoto-Kataoka S, Ebihara K, Aizawa-Abe M, Nishio M, Kusakabe T, Yamamoto Y, et al.
Horm Metab Res . 2014 Nov; 47(3):168-75. PMID: 25415231
Nonalcoholic fatty liver disease (NAFLD) is recognized as the hepatic component of the metabolic syndrome. Although NAFLD is a major cause of cirrhosis and cancer of the liver of unknown...
2.
Ebihara K, Ogawa Y, Masuzaki H, Shintani M, Miyanaga F, Aizawa-Abe M, et al.
Diabetes . 2001 May; 50(6):1440-8. PMID: 11375346
Lipoatrophic diabetes is caused by a deficiency of adipose tissue and is characterized by severe insulin resistance, hypoleptinemia, and hyperphagia. The A-ZIP/F-1 mouse (A-ZIPTg/+) is a model of severe lipoatrophic...
3.
Shintani M, Ogawa Y, Ebihara K, Aizawa-Abe M, Miyanaga F, Takaya K, et al.
Diabetes . 2001 Mar; 50(2):227-32. PMID: 11272130
Ghrelin, an endogenous ligand for growth hormone secretagogue (GHS) receptor originally isolated from the stomach, occurs in the hypothalamic arcuate nucleus and may play a role in energy homeostasis. Synthetic...
4.
Matsuoka N, Ogawa Y, Masuzaki H, Ebihara K, Aizawa-Abe M, Satoh N, et al.
Am J Physiol Endocrinol Metab . 2001 Feb; 280(2):E334-9. PMID: 11158938
Leptin is an adipocyte-derived circulating satiety factor with a variety of biological effects. Evidence has accumulated suggesting that leptin may modulate glucose and lipid metabolism. In the present study, we...
5.
Aizawa-Abe M, Ogawa Y, Masuzaki H, Nakao K
Nihon Rinsho . 2000 Oct; 58 Suppl 1:551-5. PMID: 11026331
No abstract available.
6.
Aizawa-Abe M, Ogawa Y, Masuzaki H, Ebihara K, Satoh N, Iwai H, et al.
J Clin Invest . 2000 May; 105(9):1243-52. PMID: 10791999
To explore the pathophysiological role of leptin in obesity-related hypertension, we examined cardiovascular phenotypes of transgenic skinny mice whose elevated plasma leptin concentrations are comparable to those seen in obese...
7.
Yura S, Ogawa Y, Sagawa N, Masuzaki H, Itoh H, Ebihara K, et al.
J Clin Invest . 2000 Mar; 105(6):749-55. PMID: 10727443
Excess or loss of body fat can be associated with infertility, suggesting that adequate fat mass is essential for proper reproductive function. Leptin is an adipocyte-derived hormone that is involved...
8.
Ebihara K, Ogawa Y, Katsuura G, Numata Y, Masuzaki H, Satoh N, et al.
Diabetes . 1999 Oct; 48(10):2028-33. PMID: 10512369
To understand the role of agouti-related protein (AGRP), an endogenous antagonist of hypothalamic melanocortin receptor, in leptin action, we produced a full-length recombinant AGRP and examined its effect on the...
9.
Ogawa Y, Masuzaki H, Hosoda K, Aizawa-Abe M, Suga J, Suda M, et al.
Diabetes . 1999 Sep; 48(9):1822-9. PMID: 10480614
Excess of body fat, or obesity, is a major health problem and confers a higher risk of cardiovascular and metabolic disorders such as diabetes, hypertension, and coronary heart disease. Leptin...
10.
Masuzaki H, Ogawa Y, Aizawa-Abe M, Hosoda K, Suga J, Ebihara K, et al.
Diabetes . 1999 Jul; 48(8):1615-22. PMID: 10426381
Leptin acts as an adipocyte-derived blood-borne satiety factor that can increase glucose metabolism. To elucidate the therapeutic implications of leptin for obesity-associated diabetes, we crossed transgenic skinny mice overexpressing leptin...