M A Haughton

Overview

Explore the profile of M A Haughton including associated specialties, affiliations and a list of published articles.

Snapshot

Articles 9

Citations 82

Followers 0

Related Specialties

Biochemistry

Anesthesiology

Biophysics

Top 10 Co-Authors

R A Capaldi

R Aggeler

H L Impey

T L Applegate

A V Todd

C J Fuery

M A Brown

D J Bihari

J A Eisman

S F Grant

Published In

J Biol Chem

Clin Chem

Biochim Biophys Acta

Anal Biochem

Anaesth Intensive Care

Affiliations

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Recent Articles

Genetic control of bone density and turnover: role of the collagen 1alpha1, estrogen receptor, and vitamin D receptor genes

Brown M, Haughton M, Grant S, Gunnell A, Henderson N, Eisman J

J Bone Miner Res . 2001 Apr; 16(4):758-64. PMID: 11316004

Genetic factors are known to influence both the peak bone mass and probably the rate of change in bone density. A range of regulatory and structural genes has been proposed...

Factors that influence deoxyribozyme cleavage during polymerase chain reaction

Impey H, Applegate T, Haughton M, Fuery C, King J, Todd A

Anal Biochem . 2000 Nov; 286(2):300-3. PMID: 11067755

No abstract available.

DzyNA-PCR: use of DNAzymes to detect and quantify nucleic acid sequences in a real-time fluorescent format

Todd A, Fuery C, Impey H, Applegate T, Haughton M

Clin Chem . 2000 May; 46(5):625-30. PMID: 10794743

Background: DzyNA-PCR is a general strategy for the detection and quantification of specific genetic sequences associated with disease or the presence of foreign agents. The method allows homogeneous gene amplification...

The Escherichia coli F1-ATPase mutant beta Tyr-297-->Cys: functional studies and asymmetry of the enzyme under various nucleotide conditions based on reaction of the introduced Cys with N-ethylmaleimide and 7-chloro-4-nitrobenzofurazan

Haughton M, Capaldi R

Biochim Biophys Acta . 1996 Sep; 1276(2):154-60. PMID: 8816947

Conversion of residue beta Tyr-297 of the Escherichia coli F1-ATPase (ECF1) to a Cys in the mutant beta Y297C led to impaired oxidative phosphorylation based on growth curves. The ATPase...

Conformational changes in the Escherichia coli ATP synthase (ECF1F0) monitored by nucleotide-dependent differences in the reactivity of Cys-87 of the gamma subunit in the mutant betaGlu-381 --> Ala

Feng Z, Aggeler R, Haughton M, Capaldi R

J Biol Chem . 1996 Jul; 271(30):17986-9. PMID: 8663500

Cys-87, one of two intrinsic cysteines of the gamma subunit of the Escherichia coli ATP synthase (ECF1F0), is in a short segment of this subunit that binds to the bottom...

Asymmetry of Escherichia coli F1-ATPase as a function of the interaction of alpha-beta subunit pairs with the gamma and epsilon subunits

Haughton M, Capaldi R

J Biol Chem . 1995 Sep; 270(35):20568-74. PMID: 7657634

The asymmetry of Escherichia coli F1-ATPase (ECF1) has been explored in chemical modification experiments involving two mutant enzyme preparations. One mutant contains a cysteine (Cys) at position 149 of the...

Disulfide bond formation between the COOH-terminal domain of the beta subunits and the gamma and epsilon subunits of the Escherichia coli F1-ATPase. Structural implications and functional consequences

Aggeler R, Haughton M, Capaldi R

J Biol Chem . 1995 Apr; 270(16):9185-91. PMID: 7721834

A set of mutants of the Escherichia coli F1F0-type ATPase has been generated by site-directed mutagenesis as follows: beta E381C, beta S383C, beta E381C/epsilon S108C, and beta S383C/epsilon S108C. Treatment...

A comparison between direct and calculated oxygen saturation in intensive care

Johnson P, Bihari D, Raper R, Haughton M, Fisher M, Herkes R

Anaesth Intensive Care . 1993 Feb; 21(1):72-5. PMID: 8447611

We investigated the discrepancy between calculated and spectrophotometrically determined oxygen saturation, and the corresponding effect of this difference on calculated oxygen uptake in 46 arterial-venous sample pairs from 28 critically...

Immunonephelometric assay of vitamin D-binding protein

Haughton M, Mason R

Clin Chem . 1992 Sep; 38(9):1796-801. PMID: 1526017

An automated immunonephelometric assay was developed to measure vitamin D-binding protein (DBP) in serum. The assay is described for the Behring Nephelometer System, which uses rabbit anti-DBP antiserum and purified...