A V Todd
Overview
Explore the profile of A V Todd including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
192
Followers
0
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Recent Articles
1.
Todd A, Iland H
Leuk Lymphoma
. 2016 Jul;
3(4):293-300.
PMID: 27464250
We have developed a rapid screening method for analysis of codon 12, 13 and 61 N-ras gene mutations, since these mutations have been observed in approximately 25% of patients with...
2.
End D, Smets G, Todd A, Applegate T, Fuery C, Angibaud P, et al.
Cancer Res
. 2001 Feb;
61(1):131-7.
PMID: 11196150
R115777 [(B)-6-[amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)-methyl]-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone] is a potent and selective inhibitor of farnesyl protein transferase with significant antitumor effects in vivo subsequent to oral administration in mice. In vitro, using isolated human farnesyl...
3.
Impey H, Applegate T, Haughton M, Fuery C, King J, Todd A
Anal Biochem
. 2000 Nov;
286(2):300-3.
PMID: 11067755
No abstract available.
4.
Todd A, Fuery C, Impey H, Applegate T, Haughton M
Clin Chem
. 2000 May;
46(5):625-30.
PMID: 10794743
Background: DzyNA-PCR is a general strategy for the detection and quantification of specific genetic sequences associated with disease or the presence of foreign agents. The method allows homogeneous gene amplification...
5.
Fuery C, Impey H, Roberts N, Applegate T, Ward R, Hawkins N, et al.
Clin Chem
. 2000 May;
46(5):620-4.
PMID: 10794742
Background: Restriction endonuclease-mediated selective (REMS)-PCR, allows detection of point mutations, deletions, and insertions. Reactions require concurrent activity of a restriction endonuclease (RE) and a DNA polymerase, both of which must...
6.
Roberts N, Impey H, Applegate T, Fuery C, Ward R, Todd A
Biotechniques
. 1999 Sep;
27(3):418-20, 422.
PMID: 10489596
No abstract available.
7.
Ward R, Todd A, Santiago F, OConnor T, Hawkins N
Cancer
. 1997 Mar;
79(6):1106-13.
PMID: 9070487
Background: Recent in vitro data indicate that the oncogenic effects of activated ras genes may be mediated, at least in part, through inhibition of apoptotic cell death. To examine this...
8.
SANTIAGO F, Todd A, Hawkins N, Ward R
Mol Cell Probes
. 1997 Feb;
11(1):33-8.
PMID: 9076712
Point mutations in the K-ras gene are frequently observed in a variety of human malignancies, including colorectal and pancreatic cancers. In this paper, we describe a sensitive procedure for the...
9.
Ward R, Santiago F, Hawkins N, Coomber D, OConnor T, Todd A
Clin Mol Pathol
. 1995 Oct;
48(5):M273-7.
PMID: 16696021
Aims-To develop a rapid PCR ELISA procedure for the detection of mutations in K-ras in a microtitre plate format, and to evaluate the assay for the detection of these mutations...
10.
Thorn J, Todd A, Croaker G, Iland H
Leuk Res
. 1993 Jan;
17(1):23-9.
PMID: 8429676
A mutant human N-ras gene (codon 61, C to A substitution) was electroporated into the human leukemic cell line K562, originally derived from a patient with chronic myeloid leukemia (CML)...