M A Ator
Overview
Explore the profile of M A Ator including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
220
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Recent Articles
1.
Tripathy R, Ator M, Mallamo J
Bioorg Med Chem Lett
. 2000 Oct;
10(20):2315-9.
PMID: 11055346
A series of irreversible inhibitors of recombinant calpain has been synthesized and their rates of inactivation have been evaluated against calpain and cathepsin B, respectively. The design of the inhibitors...
2.
Chatterjee S, Dunn D, Mallya S, Ator M
Bioorg Med Chem Lett
. 1999 Sep;
9(17):2603-6.
PMID: 10498217
A series of potent P'-extended alpha-ketoamide inhibitors of chymotrypsin-like activity of proteasome is described.
3.
Chatterjee S, Dunn D, Tao M, Wells G, Gu Z, Bihovsky R, et al.
Bioorg Med Chem Lett
. 1999 Sep;
9(16):2371-4.
PMID: 10476871
A series of potent P2-achiral, P'-extended alpha-ketoamide inhibitors of calpain I is described.
4.
Tripathy R, Gu Z, Dunn D, Senadhi S, Ator M, Chatterjee S
Bioorg Med Chem Lett
. 1999 Jan;
8(19):2647-52.
PMID: 9873596
The syntheses and biological activities of a series of calpain I inhibitors, derived from D- and L-Pro, are described.
5.
Mallya S, Meyer S, Bozyczko-Coyne D, Siman R, Ator M
Biochem Biophys Res Commun
. 1998 Jul;
248(2):293-6.
PMID: 9675129
We have developed a sensitive and continuously recording fluorogenic assay for the thiol protease calpain. This assay uses the dipeptide substrate Suc-Leu-Tyr-4-Methoxy-2-Naphthylamine (Suc-LY-MNA) in Tris buffer (pH 7.5) in the...
6.
Chatterjee S, Gu Z, Dunn D, Tao M, Josef K, Tripathy R, et al.
J Med Chem
. 1998 Jul;
41(15):2663-6.
PMID: 9667954
No abstract available.
7.
Chatterjee S, Ator M, Bozyczko-Coyne D, Josef K, Wells G, Tripathy R, et al.
J Med Chem
. 1997 Nov;
40(23):3820-8.
PMID: 9371247
Calpain I, an intracellular cysteine protease, has been implicated in the neurodegeneration following an episode of stroke. In this paper, we report on a series of potent dipeptide fluoromethyl ketone...
8.
Dolle R, Prasad C, Prouty C, Salvino J, Awad M, Schmidt S, et al.
J Med Chem
. 1997 Jun;
40(13):1941-6.
PMID: 9207934
No abstract available.
9.
Dolle R, Prouty C, Prasad C, Cook E, Saha A, Ross T, et al.
J Med Chem
. 1996 Jun;
39(13):2438-40.
PMID: 8691439
No abstract available.
10.
Malinowski J, Grasberger B, Trakshel G, Huston E, Helaszek C, Smallwood A, et al.
Protein Sci
. 1995 Oct;
4(10):2149-55.
PMID: 8535252
Interleukin-1 beta converting enzyme (ICE) is a cysteine protease that catalyzes the conversion of the inactive precursor form of IL-1 beta to an active mature form. The mature form of...