Lyndsay M Stapleton
Overview
Explore the profile of Lyndsay M Stapleton including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
521
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Recent Articles
1.
Wang H, Wisneski A, Imbrie-Moore A, Paulsen M, Wang Z, Xuan Y, et al.
J Mech Behav Biomed Mater
. 2022 Jan;
126:105074.
PMID: 35030471
After myocardial infarction (MI), adult mammals exhibit scar formation, adverse left ventricular (LV) remodeling, LV stiffening, and impaired contractility, ultimately resulting in heart failure. Neonatal mammals, however, are capable of...
2.
Correa S, Grosskopf A, Lopez Hernandez H, Chan D, Yu A, Stapleton L, et al.
Chem Rev
. 2021 May;
121(18):11385-11457.
PMID: 33938724
Advances in hydrogel technology have unlocked unique and valuable capabilities that are being applied to a diverse set of translational applications. Hydrogels perform functions relevant to a range of biomedical...
3.
Lal R, Maikawa C, Lewis D, Baker S, Smith A, Roth G, et al.
Clin Transl Med
. 2021 May;
11(4):e387.
PMID: 33931977
Understanding how automated insulin delivery (AID) algorithm features impact glucose control under full closed loop delivery represents a critical step toward reducing patient burden by eliminating the need for carbohydrate...
4.
Mann J, Maikawa C, Smith A, Grosskopf A, Baker S, Roth G, et al.
Sci Transl Med
. 2020 Jul;
12(550).
PMID: 32611683
Insulin has been used to treat diabetes for almost 100 years; yet, current rapid-acting insulin formulations do not have sufficiently fast pharmacokinetics to maintain tight glycemic control at mealtimes. Dissociation...
5.
Williams K, Wang H, Paulsen M, Thakore A, Rieck M, Lucian H, et al.
Microb Biotechnol
. 2020 Jun;
13(6):1780-1792.
PMID: 32476224
The cyanobacterium Synechococcus elongatus (SE) has been shown to rescue ischaemic heart muscle after myocardial infarction by photosynthetic oxygen production. Here, we investigated SE toxicity and hypothesized that systemic SE...
6.
Maikawa C, Smith A, Zou L, Roth G, Gale E, Stapleton L, et al.
Nat Biomed Eng
. 2020 May;
4(5):507-517.
PMID: 32393892
Treatment of patients with diabetes with insulin and pramlintide (an amylin analogue) is more effective than treatment with insulin only. However, because mixtures of insulin and pramlintide are unstable and...
7.
Wang H, Bennett-Kennett R, Paulsen M, Hironaka C, Thakore A, Farry J, et al.
Sci Rep
. 2020 May;
10(1):7319.
PMID: 32355240
Neonatal mice exhibit natural heart regeneration after myocardial infarction (MI) on postnatal day 1 (P1), but this ability is lost by postnatal day 7 (P7). Cardiac biomechanics intricately affect long-term...
8.
Steele A, Paulsen M, Wang H, Stapleton L, Lucian H, Eskandari A, et al.
Cytokine
. 2020 Jan;
127:154974.
PMID: 31978642
Although ischemic heart disease is the leading cause of death worldwide, mainstay treatments ultimately fail because they do not adequately address disease pathophysiology. Restoring the microvascular perfusion deficit remains a...
9.
Wang H, Paulsen M, Hironaka C, Shin H, Farry J, Thakore A, et al.
Cells
. 2020 Jan;
9(1).
PMID: 31963369
Newborn mice and piglets exhibit natural heart regeneration after myocardial infarction (MI). Discovering other mammals with this ability would provide evidence that neonatal cardiac regeneration after MI may be a...
10.
Yu A, Lopez Hernandez H, Kim A, Stapleton L, Brand R, Mellor E, et al.
Proc Natl Acad Sci U S A
. 2019 Oct;
116(42):20820-20827.
PMID: 31570592
Polyphosphate fire retardants are a critical tactical resource for fighting fires in the wildland and in the wildland-urban interface. Yet, application of these retardants is limited to emergency suppression strategies...