Lyndsay M Stapleton
Overview
Explore the profile of Lyndsay M Stapleton including associated specialties, affiliations and a list of published articles.
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18
Citations
521
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Recent Articles
11.
Stapleton L, Steele A, Wang H, Lopez Hernandez H, Yu A, Paulsen M, et al.
Nat Biomed Eng
. 2019 Aug;
3(8):611-620.
PMID: 31391596
Post-operative adhesions form as a result of normal wound healing processes following any type of surgery. In cardiac surgery, pericardial adhesions are particularly problematic during reoperations, as surgeons must release...
12.
Wang H, Wisneski A, Paulsen M, Imbrie-Moore A, Wang Z, Xuan Y, et al.
J Mech Behav Biomed Mater
. 2019 Apr;
96:165-171.
PMID: 31035067
Adverse remodeling of the left ventricle (LV) after myocardial infarction (MI) results in abnormal tissue biomechanics and impaired cardiac function, often leading to heart failure. We hypothesized that intramyocardial delivery...
13.
Paulsen M, Kasinpila P, Imbrie-Moore A, Wang H, Hironaka C, Koyano T, et al.
J Thorac Cardiovasc Surg
. 2019 Feb;
158(2):392-403.
PMID: 30745047
Objective: The optimal conduit for valve-sparing aortic root replacement is still debated, with several conduit variations available, ranging from straight tubular grafts to Valsalva grafts. Benefits of neosinus reconstruction include...
14.
Steele A, Stapleton L, Farry J, Lucian H, Paulsen M, Eskandari A, et al.
Adv Healthc Mater
. 2019 Feb;
8(5):e1801147.
PMID: 30714355
Hydrogels have emerged as a diverse class of biomaterials offering a broad range of biomedical applications. Specifically, injectable hydrogels are advantageous for minimally invasive delivery of various therapeutics and have...
15.
Lopez Hernandez H, Grosskopf A, Stapleton L, Agmon G, Appel E
Macromol Biosci
. 2018 Oct;
19(1):e1800275.
PMID: 30369048
Drug delivery and cell transplantation require minimally invasive deployment strategies such as injection through clinically relevant high-gauge needles. Supramolecular hydrogels comprising dodecyl-modified hydroxypropylmethylcellulose and poly(ethylene glycol)-block-poly(lactic acid) have been previously...
16.
Kawamura M, Paulsen M, Goldstone A, Shudo Y, Wang H, Steele A, et al.
Cardiovasc Diabetol
. 2017 Nov;
16(1):142.
PMID: 29096622
Background: Diabetes mellitus is a risk factor for coronary artery disease and diabetic cardiomyopathy, and adversely impacts outcomes following coronary artery bypass grafting. Current treatments focus on macro-revascularization and neglect...
17.
Cohen J, Goldstone A, Paulsen M, Shudo Y, Steele A, Edwards B, et al.
Sci Adv
. 2017 Jun;
3(6):e1603078.
PMID: 28630913
Coronary artery disease is one of the most common causes of death and disability, afflicting more than 15 million Americans. Although pharmacological advances and revascularization techniques have decreased mortality, many...
18.
Yu A, Chen H, Chan D, Agmon G, Stapleton L, Sevit A, et al.
Proc Natl Acad Sci U S A
. 2016 Dec;
113(50):14255-14260.
PMID: 27911849
Hydrogels are a class of soft material that is exploited in many, often completely disparate, industrial applications, on account of their unique and tunable properties. Advances in soft material design...