Lupei Du
Overview
Explore the profile of Lupei Du including associated specialties, affiliations and a list of published articles.
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Articles
114
Citations
754
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Recent Articles
1.
Liang D, Yu C, Ma Z, Yang X, Li Z, Dong X, et al.
Acta Pharm Sin B
. 2024 Dec;
14(11):5089-5090.
PMID: 39664436
[This corrects the article DOI: 10.1016/j.apsb.2021.12.005.].
2.
Wang S, Li Z, Ma S, Zhang S, Guo S, Ma Z, et al.
Bioorg Chem
. 2024 Sep;
153:107801.
PMID: 39244973
Resistance to proteasome inhibitors like Bortezomib is a major challenge in the treatment of multiple myeloma (MM). Proteolysis targeting chimeras (PROTACs), an emerging therapeutic approach that induces selective degradation of...
3.
Yang X, Zhou X, Qin X, Liang D, Dong X, Ji H, et al.
ACS Pharmacol Transl Sci
. 2024 Jun;
7(6):1839-1846.
PMID: 38898952
Photopharmacology is a powerful approach to investigate biological processes and overcomes the common therapeutic challenges in drug development. Enhancing the photopharmacology properties of photoswitches contributes to extend their applications. Deuteration,...
4.
Wang S, Lei K, Lai H, Liu T, Du L, Wu S, et al.
ACS Pharmacol Transl Sci
. 2024 Apr;
7(4):1178-1190.
PMID: 38633583
A promising alternative for cancer treatment involves targeted inhibition of the epigenetic regulator bromodomain-containing protein 4 (BRD4); however, available BRD4 inhibitors are constrained by their potency, oral bioavailability, and cytotoxicity....
5.
Li Z, Ma S, Zhang S, Ma Z, Du L, Li M
Drug Discov Today
. 2023 Jul;
28(9):103716.
PMID: 37467880
Targeted protein degradation (TPD) strategies, such as proteolysis-targeting chimeras (PROTACs) only work for intracellular protein degradation because they involve the intracellular protein degradation machinery. Several new technologies have emerged in...
6.
Yang X, Li M, Qin X, Tan S, Du L, Ma C, et al.
J Am Chem Soc
. 2023 Jun;
145(25):14165-14166.
PMID: 37338414
No abstract available.
7.
Li W, Ma Z, Du L, Li M
Anal Chem
. 2023 Jan;
95(5):2848-2856.
PMID: 36700797
For the precise visualization of GPCR, subtype selectivity of turn-on fluorescent ligands is of major relevance. Although there are many thriving β-adrenergic receptors (β-ARs) probes, none of them are selective...
8.
Sun D, Dong G, Wu Y, Dong G, Du L, Li M, et al.
Eur J Med Chem
. 2023 Jan;
248:115080.
PMID: 36608458
Nicotinamide phosphoribosyl transferase (NAMPT) has been regarded as an attractive target for cancer therapy. However, there is a lack of chemical tools for real-time visualization and detection of NAMPT. Herein,...
9.
Li Z, Ma S, Zhang L, Zhang S, Ma Z, Du L, et al.
J Med Chem
. 2022 Dec;
66(1):733-751.
PMID: 36574496
Targeted protein degradation (TPD) strategies open up new avenues for therapeutics and provide powerful tools for biological inquiry. Herein, we present a brand-new approach, termed heat shock protein 90 (HSP90)-mediated...
10.
Sun Y, Gao Y, Tang C, Dong G, Zhao P, Peng D, et al.
J Pharm Anal
. 2022 Jul;
12(3):446-452.
PMID: 35811615
In recent years, various methods for detecting exogenous and endogenous hypochlorite have been studied, considering its essential role as a biomolecule. However, the existing technologies still pose obstacles such as...