Luoying Zhang
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Explore the profile of Luoying Zhang including associated specialties, affiliations and a list of published articles.
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59
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2132
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Recent Articles
1.
Gu J, Wang J, Fan H, Wei Y, Li Y, Ma C, et al.
Exp Mol Med
. 2025 Mar;
PMID: 40025170
Neuropathic pain causes enduring physical discomfort and emotional distress. Conventional pharmacological treatments often provide restricted relief and may result in undesirable side effects, posing a substantial clinical challenge. Peripheral and...
2.
Endothelial BMAL1 decline during aging leads to bone loss by destabilizing extracellular fibrillin-1
Yin Y, Tang Q, Yang J, Gui S, Zhang Y, Shen Y, et al.
J Clin Invest
. 2024 Dec;
134(24).
PMID: 39680455
The occurrence of aging is intricately associated with alterations in circadian rhythms that coincide with stem cell exhaustion. Nonetheless, the extent to which the circadian system governs skeletal aging remains...
3.
Gao Q, Tang Z, Wang H, Yamazaki M, Jiang J, Fu Y, et al.
Nat Metab
. 2024 Nov;
6(12):2267-2280.
PMID: 39528818
Our brain adapts to seasonal changes. Mis-adaptations may lead to seasonal patterns in several psychiatric disorders, but we know little regarding the underlying mechanisms. Our previous work identified two variants...
4.
Wang J, Gu J, Ma F, Wei Y, Wang P, Yang S, et al.
Research (Wash D C)
. 2024 Oct;
7:0493.
PMID: 39381792
Neuropathic pain (NP) represents a considerable clinical challenge, profoundly impacting patients' quality of life. Presently, pharmacotherapy serves as a primary approach for NP alleviation, yet its efficacy often remains suboptimal....
5.
Yu S, Tang Q, Lu X, Chen G, Xie M, Yang J, et al.
Nat Metab
. 2024 May;
6(6):1036-1052.
PMID: 38806654
Although physical training has been shown to improve bone mass, the time of day to exercise for optimal bone growth remains uncertain. Here we show that engaging in physical activity...
6.
Large-language models facilitate discovery of the molecular signatures regulating sleep and activity
Peng D, Zheng L, Liu D, Han C, Wang X, Yang Y, et al.
Nat Commun
. 2024 May;
15(1):3685.
PMID: 38693116
Sleep, locomotor and social activities are essential animal behaviors, but their reciprocal relationships and underlying mechanisms remain poorly understood. Here, we elicit information from a cutting-edge large-language model (LLM), generative...
7.
Peng D, Jia D, Xia H, Zhang L, Huang P, Xue Y
Sci Bull (Beijing)
. 2024 Feb;
69(8):989-992.
PMID: 38320898
No abstract available.
8.
Hao H, Song L, Zhang L
PLoS Genet
. 2023 Jul;
19(7):e1010827.
PMID: 37399203
Sleep disruptions are quite common in psychological disorders, but the underlying mechanism remains obscure. Wolfram syndrome 1 (WS1) is an autosomal recessive disease mainly characterized by diabetes insipidus/mellitus, neurodegeneration and...
9.
Li M, Li S, Zhang L
Research (Wash D C)
. 2023 May;
6:0139.
PMID: 37223461
Circadian clock drives the 24-h rhythm in our behavior and physiology. The molecular clock consists of a series of transcriptional/translational feedback loops operated by a number of clock genes. A...
10.
Li Y, Zhou X, Cheng C, Ding G, Zhao P, Tan K, et al.
Cell Discov
. 2023 May;
9(1):49.
PMID: 37221172
Severe sleep deprivation (SD) has been highly associated with systemic energy wasting, such as lipid loss and glycogen depletion. Despite immune dysregulation and neurotoxicity observed in SD animals, whether and...