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Luoying Zhang

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Recent Articles
11.
Shui K, Wang C, Zhang X, Ma S, Li Q, Ning W, et al.
Nat Commun . 2023 May; 14(1):2813. PMID: 37198164
Proteostasis is fundamental for maintaining organismal health. However, the mechanisms underlying its dynamic regulation and how its disruptions lead to diseases are largely unclear. Here, we conduct in-depth propionylomic profiling...
12.
Du S, Zeng S, Song L, Ma H, Chen R, Luo J, et al.
Sci China Life Sci . 2023 Apr; 66(9):2152-2166. PMID: 37071290
Focal epilepsy accounts for 60% of all forms of epilepsy, but the pathogenic mechanism is not well understood. In this study, three novel mutations in NPRL3 (nitrogen permease regulator-like 3),...
13.
Chen G, Tang Q, Yu S, Shen Y, Sun J, Peng J, et al.
Cell Death Differ . 2023 Apr; 30(6):1503-1516. PMID: 37029304
Exposure to artificial light at night (LAN) can induce obesity, depressive disorder and osteoporosis, but the pernicious effects of excessive LAN exposure on tissue structure are poorly understood. Here, we...
14.
Gao C, Peng X, Zhang L, Zhao Q, Ma L, Yu Q, et al.
Genes (Basel) . 2023 Mar; 14(3). PMID: 36981020
High temperatures severely affect plant growth and pose a threat to global crop production. Heat causes the accumulation of misfolded proteins in the endoplasmic reticulum(ER), as well as triggering the...
15.
Wang X, Xing K, He M, He T, Xiang X, Chen T, et al.
Natl Sci Rev . 2023 Feb; 10(1):nwac222. PMID: 36825118
High-fat diet (HFD)-induced obesity is a growing epidemic and major health concern. While excessive daytime sleepiness (EDS) is a common symptom of HFD-induced obesity, preliminary findings suggest that reduced wakefulness...
16.
Peng J, Zhao J, Tang Q, Wang J, Song W, Lu X, et al.
Int J Oral Sci . 2022 Nov; 14(1):53. PMID: 36376275
Bone regeneration remains a great clinical challenge. Low intensity near-infrared (NIR) light showed strong potential to promote tissue regeneration, offering a promising strategy for bone defect regeneration. However, the effect...
17.
Zhang L, Turck C, Wang G
Front Genet . 2022 Oct; 13:1016049. PMID: 36186477
No abstract available.
18.
Wu Y, Chen M, Chen Z, Shu J, Zhang L, Hu J, et al.
Front Pharmacol . 2022 Jul; 13:861319. PMID: 35903325
The abnormal neointima formation caused by the phenotypic switching of vascular smooth cells (VSMCs) into a synthetic state plays a key role in the pathogenesis of various vascular diseases, including...
19.
Tao X, Chen C, Chen Y, Zhang L, Hu J, Yu H, et al.
Cell Death Dis . 2022 Jun; 13(6):571. PMID: 35760785
The β-adrenergic receptor (βAR) is a G protein-coupled receptor (GPCR) that mediates the majority of cellular responses to external stimuli. Aberrant expression of βAR results in various pathophysiological disorders, including...
20.
Chen R, Du S, Yao Y, Zhang L, Luo J, Shen Y, et al.
Mov Disord . 2021 Dec; 37(3):598-607. PMID: 34927746
Background: Haploinsufficiency is widely accepted as the pathogenic mechanism of spastic paraplegia type 4 (SPG4). However, there are some cases that cannot be explained by reduced function of the spastin...