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Luna Jimenez-Castilla

Explore the profile of Luna Jimenez-Castilla including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 150
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Recent Articles
1.
Prieto I, Kavanagh M, Jimenez-Castilla L, Pardines M, Lazaro I, Herrero Del Real I, et al.
Mol Ther Nucleic Acids . 2023 Oct; 34:102041. PMID: 37842165
Diabetic kidney disease (DKD) is a common microvascular complication of diabetes, a global health issue. Hyperglycemia, in concert with cytokines, activates the Janus kinase (JAK)/signal transducer and activator of transcription...
2.
Lopez-Sanz L, Bernal S, Jimenez-Castilla L, Pardines M, Hernandez-Garcia A, Blanco-Colio L, et al.
Clin Investig Arterioscler . 2023 Feb; 35(4):185-194. PMID: 36737385
Introduction: Abdominal aortic aneurysm (AAA) is a multifactorial, degenerative disease characterized by progressive aortic dilation and chronic activation of inflammation, proteolytic activity, and oxidative stress in the aortic wall. The...
3.
Jimenez-Castilla L, Opazo-Rios L, Marin-Royo G, Orejudo M, Rodrigues-Diez R, Ballesteros-Martinez C, et al.
Antioxidants (Basel) . 2022 Dec; 11(12). PMID: 36552707
In diabetes, chronic hyperglycemia, dyslipidemia, inflammation and oxidative stress contribute to the progression of macro/microvascular complications. Recently, benefits of the use of flavonoids in these conditions have been established. This...
4.
Opazo-Rios L, Soto-Catalan M, Lazaro I, Sala-Vila A, Jimenez-Castilla L, Orejudo M, et al.
Int J Mol Sci . 2022 Apr; 23(7). PMID: 35409324
Metabolic associated fatty liver disease (MAFLD) is a hepatic manifestation of metabolic syndrome and usually associated with obesity and diabetes. Our aim is to characterize the pathophysiological mechanism involved in...
5.
Jimenez-Castilla L, Marin-Royo G, Orejudo M, Opazo-Rios L, Caro-Ordieres T, Artaiz I, et al.
Antioxidants (Basel) . 2021 Dec; 10(12). PMID: 34943023
Diabetes mellitus (DM) is a high-impact disease commonly characterized by hyperglycemia, inflammation, and oxidative stress. Diabetic nephropathy (DN) is a common diabetic microvascular complication and the leading cause of chronic...
6.
Lopez-Sanz L, Bernal S, Jimenez-Castilla L, Prieto I, La Manna S, Gomez-Lopez S, et al.
Clin Transl Med . 2021 Jul; 11(7):e463. PMID: 34323424
Background: Abdominal aortic aneurysm (AAA), a degenerative vascular pathology characterized by permanent dilation of the aorta, is considered a chronic inflammatory disease involving innate/adaptive immunity. However, the functional role of...
7.
Bernal S, Lopez-Sanz L, Jimenez-Castilla L, Prieto I, Melgar A, La Manna S, et al.
Br J Pharmacol . 2020 Nov; 178(3):564-581. PMID: 33227156
Background And Purpose: Abdominal aortic aneurysm (AAA) is a multifactorial disease characterized by chronic inflammation, oxidative stress and proteolytic activity in the aortic wall. Targeting JAK/signal transducer and activator of...
8.
La Manna S, Lopez-Sanz L, Bernal S, Jimenez-Castilla L, Prieto I, Morelli G, et al.
Antioxidants (Basel) . 2020 Aug; 9(8). PMID: 32824091
The chronic activation of the Janus kinase/signal transducer and activator of the transcription (JAK/STAT) pathway is linked to oxidative stress, inflammation and cell proliferation. Suppressors of cytokine signaling (SOCS) proteins...
9.
Opazo-Rios L, Plaza A, Sanchez Matus Y, Bernal S, Lopez-Sanz L, Jimenez-Castilla L, et al.
Int J Mol Sci . 2020 Jun; 21(12). PMID: 32545818
Diabetic nephropathy (DN) is a multifactorial disease characterized by hyperglycemia and close interaction of hemodynamic, metabolic and inflammatory factors. Nuclear factor-κB (NF-κB) is a principal matchmaker linking hyperglycemia and inflammation....
10.
Caro-Ordieres T, Marin-Royo G, Opazo-Rios L, Jimenez-Castilla L, Moreno J, Gomez-Guerrero C, et al.
J Clin Med . 2020 Feb; 9(2). PMID: 32012726
Diabetes mellitus (DM), and its micro and macrovascular complications, is one of the biggest challenges for world public health. Despite overall improvement in prevention, diagnosis and treatment, its incidence is...