Luke Jostins
Overview
Explore the profile of Luke Jostins including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
40
Citations
9414
Followers
0
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
31.
Liu J, Almarri M, Gaffney D, Mells G, Jostins L, Cordell H, et al.
Nat Genet
. 2012 Sep;
44(10):1137-41.
PMID: 22961000
We genotyped 2,861 cases of primary biliary cirrhosis (PBC) from the UK PBC Consortium and 8,514 UK population controls across 196,524 variants within 186 known autoimmune risk loci. We identified...
32.
Jostins L
Genome Biol
. 2012 Jun;
13(6):316.
PMID: 22738333
A report on the 25th annual meeting on The Biology of Genomes, Cold Spring Harbor, USA, 8-12 May 2012.
33.
Jostins L, Pickrell J, MacArthur D, Barrett J
Proc Natl Acad Sci U S A
. 2012 Apr;
109(18):E1048.
PMID: 22499788
No abstract available.
34.
Sewell G, Rahman F, Levine A, Jostins L, Smith P, Walker A, et al.
Inflamm Bowel Dis
. 2012 Mar;
18(11):2120-7.
PMID: 22434667
Background: Recent work provides evidence of a failure of acute inflammation in Crohn's disease (CD), and suggests that the primary defect operates at the level of the macrophage and cytokine...
35.
MacArthur D, Balasubramanian S, Frankish A, Huang N, Morris J, Walter K, et al.
Science
. 2012 Feb;
335(6070):823-8.
PMID: 22344438
Genome-sequencing studies indicate that all humans carry many genetic variants predicted to cause loss of function (LoF) of protein-coding genes, suggesting unexpected redundancy in the human genome. Here we apply...
36.
Jostins L, Barrett J
Hum Mol Genet
. 2011 Aug;
20(R2):R182-8.
PMID: 21873261
Attempting to classify patients into high or low risk for disease onset or outcomes is one of the cornerstones of epidemiology. For some (but by no means all) diseases, clinically...
37.
Jostins L, Morley K, Barrett J
Eur J Hum Genet
. 2011 Mar;
19(6):662-6.
PMID: 21364697
Imputation allows the inference of unobserved genotypes in low-density data sets, and is often used to test for disease association at variants that are poorly captured by standard genotyping chips...
38.
Franke A, McGovern D, Barrett J, Wang K, Radford-Smith G, Ahmad T, et al.
Nat Genet
. 2010 Nov;
42(12):1118-25.
PMID: 21102463
We undertook a meta-analysis of six Crohn's disease genome-wide association studies (GWAS) comprising 6,333 affected individuals (cases) and 15,056 controls and followed up the top association signals in 15,694 cases,...
39.
Jostins L, Jaeger J
BMC Syst Biol
. 2010 Mar;
4:17.
PMID: 20196855
Background: The use of reverse engineering methods to infer gene regulatory networks by fitting mathematical models to gene expression data is becoming increasingly popular and successful. However, increasing model complexity...
40.
Krawitz P, Rodelsperger C, Jager M, Jostins L, Bauer S, Robinson P
Bioinformatics
. 2010 Feb;
26(6):722-9.
PMID: 20144947
Motivation: Several recent studies have demonstrated the effectiveness of resequencing and single nucleotide variant (SNV) detection by deep short-read sequencing platforms. While several reliable algorithms are available for automated SNV...