Luke Gammon
Overview
Explore the profile of Luke Gammon including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
23
Citations
671
Followers
0
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Related Specialties
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Top 10 Co-Authors
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Recent Articles
1.
Youssef G, Gammon L, Ambler L, Lunetto S, Scemama A, Cottom H, et al.
Elife
. 2023 Nov;
12.
PMID: 37975646
Cancer stem cells (CSCs) undergo epithelial-mesenchymal transition (EMT) to drive metastatic dissemination in experimental cancer models. However, tumour cells undergoing EMT have not been observed disseminating into the tissue surrounding...
2.
Murray A, Gough G, Cindric A, Vuckovic F, Koschut D, Borelli V, et al.
EBioMedicine
. 2023 Jul;
94:104692.
PMID: 37451904
Background: People with Down syndrome (DS) show clinical signs of accelerated ageing. Causative mechanisms remain unknown and hypotheses range from the (essentially untreatable) amplified-chromosomal-instability explanation, to potential actions of individual...
3.
Palmer A, Epton S, Crawley E, Straface M, Gammon L, Edgar M, et al.
Front Neurosci
. 2021 Oct;
15:747067.
PMID: 34690683
Human colonic neuromuscular functions decline among the elderly. The aim was to explore the involvement of senescence. A preliminary PCR study looked for age-dependent differences in expression of (encoding the...
4.
Huang Y, Jedlickova H, Cai Y, Rehman A, Gammon L, Ahmad U, et al.
Front Immunol
. 2021 May;
12:649502.
PMID: 33968042
(PV) is a life-threatening autoimmune disease manifested with blisters in the skin and mucosa and caused by autoantibodies against adhesion protein desmoglein-3 (Dsg3) expressed in epithelial membrane linings of these...
5.
Almeida F, Gammon L, Laly A, Pundel O, Bishop C, Connelly J
Adv Biosyst
. 2020 Jul;
3(8):e1900011.
PMID: 32648701
Cell migration is a fundamental biological process that is dynamically regulated by complex interactions between the microenvironment and intrinsic gene expression programs. Here, a high-throughput cell migration assay is developed...
6.
Patel A, Garcia L, Mannella V, Gammon L, Borg T, Maffucci T, et al.
Cancer Res
. 2020 Apr;
80(12):2676-2688.
PMID: 32291316
Targeting the MAPK pathway by combined inhibition of BRAF and MEK has increased overall survival in advanced BRAF-mutant melanoma in both therapeutic and adjuvant clinical settings. However, a significant proportion...
7.
Ali L, Saxena G, Jones M, Leisegang G, Gammon L, Gnanapavan S, et al.
Biotechniques
. 2020 Feb;
68(4):185-190.
PMID: 32096651
The humanized anti-CD52 monoclonal antibody alemtuzumab depletes lymphocytes and is currently used to treat relapsing multiple sclerosis. During treatment, anti-alemtuzumab antibodies may develop and reduce effective lymphocyte depletion in future...
8.
Rodrigues M, Gammon L, Rahman M, Biddle A, Nunes F, Mackenzie I
Oncotarget
. 2018 Mar;
9(17):13488-13500.
PMID: 29568372
The therapeutic responses of many solid tumours to chemo- and radio-therapies are far from fully effective but therapies targeting malignancy-related cellular changes show promise for further control. In head and...
9.
Nijhuis A, Thompson H, Adam J, Parker A, Gammon L, Lewis A, et al.
Hum Mol Genet
. 2017 Feb;
26(8):1552-1564.
PMID: 28207045
Solid tumours have oxygen gradients and areas of near and almost total anoxia. Hypoxia reduces sensitivity to 5-fluorouracil (5-FU)-chemotherapy for colorectal cancer (CRC). MicroRNAs (miRNAs) are hypoxia sensors and were...
10.
Biddle A, Gammon L, Liang X, Costea D, Mackenzie I
EBioMedicine
. 2016 Mar;
4:138-45.
PMID: 26981578
Cancer stem cells (CSCs) drive tumour spread and therapeutic resistance, and can undergo epithelial-to-mesenchymal transition (EMT) and mesenchymal-to-epithelial transition (MET) to switch between epithelial and post-EMT sub-populations. Examining oral squamous...