Lukas Trantirek
Overview
Explore the profile of Lukas Trantirek including associated specialties, affiliations and a list of published articles.
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77
Citations
1169
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Recent Articles
1.
Rynes J, Istvankova E, Dzurov Krafcikova M, Luchinat E, Barbieri L, Banci L, et al.
Commun Biol
. 2025 Feb;
8(1):194.
PMID: 39920376
Most of our knowledge of protein structure and function originates from experiments performed with purified proteins resuspended in dilute, buffered solutions. However, most proteins function in crowded intracellular environments with...
2.
Zlinska V, Feketova Z, Czyrek A, Chudzian J, Zivkovic M, Ursachi V, et al.
Mol Ther Nucleic Acids
. 2025 Jan;
36(1):102405.
PMID: 39759879
Impaired fibroblast growth factor receptor (FGFR) signaling is associated with many human conditions, including growth disorders, degenerative diseases, and cancer. Current FGFR therapeutics are based on chemical inhibitors of FGFR...
3.
Basu P, Kejnovska I, Gajarsky M, Subert D, Mikesova T, Renciuk D, et al.
Nucleic Acids Res
. 2024 Nov;
52(21):13224-13242.
PMID: 39494519
G-quadruplexes (G4s) formed within RNA are emerging as promising targets for therapeutic intervention in cancer, neurodegenerative disorders and infectious diseases. Sequences containing a succession of short GG blocks, or uneven...
4.
Schwalbe H, Audergon P, Haley N, Amaro C, Agirre J, Baldus M, et al.
Structure
. 2024 Sep;
32(10):1563-1580.
PMID: 39293444
Instruct-ERIC, "the European Research Infrastructure Consortium for Structural biology research," is a pan-European distributed research infrastructure making high-end technologies and methods in structural biology available to users. Here, we describe...
5.
Pipier A, Chetot T, Kalamatianou A, Martin N, Caroff M, Britton S, et al.
Angew Chem Int Ed Engl
. 2024 Jun;
63(36):e202409780.
PMID: 38873877
Transient melting of the duplex-DNA (B-DNA) during DNA transactions allows repeated sequences to fold into non-B-DNA structures, including DNA junctions and G-quadruplexes. These noncanonical structures can act as impediments to...
6.
Viskova P, Istvankova E, Rynes J, Dzatko S, Loja T, Zivkovic M, et al.
Nat Commun
. 2024 Mar;
15(1):1992.
PMID: 38443388
I-Motifs (iM) are non-canonical DNA structures potentially forming in the accessible, single-stranded, cytosine-rich genomic regions with regulatory roles. Chromatin, protein interactions, and intracellular properties seem to govern iM formation at...
7.
Gajarsky M, Stadlbauer P, Sponer J, Cucchiarini A, Dobrovolna M, Brazda V, et al.
Angew Chem Int Ed Engl
. 2023 Dec;
63(7):e202313226.
PMID: 38143239
DNA quadruplex structures provide an additional layer of regulatory control in genome maintenance and gene expression and are widely used in nanotechnology. We report the discovery of an unprecedented tetrastranded...
8.
Luo Y, Zivkovic M, Wang J, Rynes J, Foldynova-Trantirkova S, Trantirek L, et al.
Nucleic Acids Res
. 2023 Nov;
52(1):448-461.
PMID: 37986223
Metal ions are essential components for the survival of living organisms. For most species, intracellular and extracellular ionic conditions differ significantly. As G-quadruplexes (G4s) are ion-dependent structures, changes in the...
9.
Mergny J, Trantirek L, Capranico G
Biochimie
. 2023 Sep;
214(Pt A):1-4.
PMID: 37748749
No abstract available.
10.
Dzurov M, Pospisilova S, Krafcikova M, Trantirek L, Vojtova L, Rynes J
J Biomol NMR
. 2023 Sep;
77(5-6):203-215.
PMID: 37688760
Introducing the flow through the bioreactor has revolutionized in-cell NMR spectroscopy by prolonging the measurement time available to acquire spectral information about biomacromolecules in metabolically active cells. Bioreactor technology relies...