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Lukas Niederreiter

Explore the profile of Lukas Niederreiter including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 1065
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Recent Articles
1.
Schwarzler J, Mayr L, Vich Vila A, Grabherr F, Niederreiter L, Philipp M, et al.
Gastroenterology . 2022 Jan; 162(6):1690-1704. PMID: 35031299
Background & Aims: Crohn's disease (CD) globally emerges with Westernization of lifestyle and nutritional habits. However, a specific dietary constituent that comprehensively evokes gut inflammation in human inflammatory bowel diseases...
2.
Burkert F, Niederreiter L, Dichtl W, Mayr A, Virgolini I, Klauser A, et al.
Eur Heart J Case Rep . 2021 Feb; 5(2):ytaa521. PMID: 33598613
Background: Since the first documented outbreak of a novel severe acute respiratory syndrome inducing Coronavirus in China at the end of 2019 the virus has spread to all continents, leading...
3.
Schmiderer A, Schwaighofer H, Niederreiter L, Profanter C, Steinle H, Ziachehabi A, et al.
Endoscopy . 2020 May; 52(11):1036-1038. PMID: 32408356
Background: COVID-19 has spread rapidly around the world. The Austrian government implemented a lockdown on 16 March to contain further spread of the disease. We investigated the effects of lockdown...
4.
Mayr L, Grabherr F, Schwarzler J, Reitmeier I, Sommer F, Gehmacher T, et al.
Nat Commun . 2020 Apr; 11(1):1775. PMID: 32286299
The increased incidence of inflammatory bowel disease (IBD) has become a global phenomenon that could be related to adoption of a Western life-style. Westernization of dietary habits is partly characterized...
5.
Niederreiter L, Adolph T, Tilg H
Dig Liver Dis . 2018 Apr; 50(7):647-652. PMID: 29705028
You are what you eat. This adage has been confirmed by many studies demonstrating the high impact of nutrition on risk of cardiovascular diseases, many malignancies and other diseases. Dietary...
6.
Tschurtschenthaler M, Adolph T, Ashcroft J, Niederreiter L, Bharti R, Saveljeva S, et al.
J Exp Med . 2017 Jan; 214(2):401-422. PMID: 28082357
ATG16L1, a major risk polymorphism in Crohn's disease (CD), causes impaired autophagy, but it has remained unclear how this predisposes to CD. In this study, we report that mice with...
7.
Teschendorff A, Lee S, Jones A, Fiegl H, Kalwa M, Wagner W, et al.
Genome Med . 2015 Oct; 7:108. PMID: 26497652
Background: Understanding carboplatin resistance in ovarian cancer is critical for the improvement of patients' lives. Multipotent mesenchymal stem cells or an aggravated epithelial to mesenchymal transition phenotype of a cancer...
8.
Tschurtschenthaler M, Wang J, Fricke C, Fritz T, Niederreiter L, Adolph T, et al.
Gut . 2014 Feb; 63(12):1921-31. PMID: 24555997
Objective: Intestinal epithelial cells (IECs) at the internal/external interface orchestrate the mucosal immune response. Paneth cells secrete antimicrobial peptides and inflammatory mediators, protect from pathogens and shape the commensal microbiota....
9.
Niederreiter L, Adolph T, Kaser A
Curr Drug Targets . 2013 Oct; 14(12):1379-84. PMID: 24138637
The heterodimeric cytokines IL-12 and IL-23 play a key role in T helper cell and innate lymphocyte cell differentiation and expansion. They are composed of a shared p40 chain, which...
10.
Adolph T, Tomczak M, Niederreiter L, Ko H, Bock J, Martinez-Naves E, et al.
Nature . 2013 Oct; 503(7475):272-6. PMID: 24089213
The recognition of autophagy related 16-like 1 (ATG16L1) as a genetic risk factor has exposed the critical role of autophagy in Crohn's disease. Homozygosity for the highly prevalent ATG16L1 risk...