Lukas Cermak
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Explore the profile of Lukas Cermak including associated specialties, affiliations and a list of published articles.
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19
Citations
921
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Recent Articles
1.
Dibus N, Salyova E, Kolarova K, Abdirov A, Pagano M, Stepanek O, et al.
EMBO Rep
. 2024 Sep;
25(10):4206-4225.
PMID: 39266770
SKP1-CUL1-F-box protein (SCF) ubiquitin ligases are versatile protein complexes that mediate the ubiquitination of protein substrates. The direct substrate recognition relies on a large family of F-box-domain-containing subunits. One of...
2.
Turkova T, Kokavec J, Zikmund T, Dibus N, Pimkova K, Nemec D, et al.
Commun Biol
. 2024 Feb;
7(1):244.
PMID: 38424235
The formation of hematopoietic cells relies on the chromatin remodeling activities of ISWI ATPase SMARCA5 (SNF2H) and its complexes. The Smarca5 null and conditional alleles have been used to study...
3.
Dibus N, Korinek V, Cermak L
Front Cell Dev Biol
. 2022 Jul;
10:929288.
PMID: 35813202
Alterations in the gene encoding the E3 ubiquitin ligase substrate receptor FBXO38 have been associated with several diseases, including early-onset motor neuronopathy. However, the cellular processes affected by the enzymatic...
4.
Dibus N, Zobalova E, Monleon M, Korinek V, Filipp D, Petrusova J, et al.
Front Cell Dev Biol
. 2022 Jun;
10:914053.
PMID: 35769260
The ubiquitin ligase SCF controls centromeric chromatin by promoting the degradation of the ZXDB protein. To determine the importance of this pathway during development, -deficient mice were generated. The loss...
5.
Lidak T, Baloghova N, Korinek V, Sedlacek R, Balounova J, Kasparek P, et al.
Int J Mol Sci
. 2021 Jun;
22(10).
PMID: 34065512
Multisubunit cullin-RING ubiquitin ligase 4 (CRL4)-DCAF12 recognizes the C-terminal degron containing acidic amino acid residues. However, its physiological roles and substrates are largely unknown. Purification of CRL4-DCAF12 complexes revealed a...
6.
Baloghova N, Lidak T, Cermak L
Genes (Basel)
. 2019 Oct;
10(10).
PMID: 31623112
The Wnt, TGF-β, and Notch signaling pathways are essential for the regulation of cellular polarity, differentiation, proliferation, and migration. Differential activation and mutual crosstalk of these pathways during animal development...
7.
Svadlenka J, Brazina J, Hanzlikova H, Cermak L, Andera L
Biochem Biophys Rep
. 2017 Sep;
5:246-252.
PMID: 28955830
Multifunctional adapter and chaperone protein Daxx participates in the regulation of a number of mainly transcription-related processes. Most notably in a complex with chromatin-remodelling ATPase ATRX, Daxx serves as a...
8.
Horn M, Geisen C, Cermak L, Becker B, Nakamura S, Klein C, et al.
Dev Cell
. 2014 Mar;
28(6):697-710.
PMID: 24613396
Developmental timing genes catalyze stem cell progression and animal maturation programs across taxa. Caenorhabditis elegans DRE-1/FBXO11 functions in an SCF E3-ubiquitin ligase complex to regulate the transition to adult programs,...
9.
Jeong Y, Cermak L, Guijarro M, Hernando E, Pagano M
Cell Cycle
. 2013 Mar;
12(7):1128-32.
PMID: 23466708
FBH1 is a member of the UvrD family of DNA helicases and plays a crucial role in the response to DNA replication stress. In particular, upon DNA replication stress, FBH1...
10.
Jeong Y, Rossi M, Cermak L, Saraf A, Florens L, Washburn M, et al.
J Cell Biol
. 2013 Jan;
200(2):141-9.
PMID: 23319600
Proper resolution of stalled replication forks is essential for genome stability. Purification of FBH1, a UvrD DNA helicase, identified a physical interaction with replication protein A (RPA), the major cellular...