Lukas C Heukamp
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Explore the profile of Lukas C Heukamp including associated specialties, affiliations and a list of published articles.
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105
Citations
4633
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Recent Articles
11.
Szymansky A, Kruetzfeldt L, Heukamp L, Hertwig F, Theissen J, Deubzer H, et al.
J Pers Med
. 2021 Aug;
11(8).
PMID: 34442335
For many years, the risk-based therapy stratification of children with neuroblastoma has relied on clinical and molecular covariates. In recent years, genome analysis has revealed further alterations defining risk, tumor...
12.
Meder L, Florin A, Ozretic L, Nill M, Koker M, Meemboor S, et al.
Pathol Oncol Res
. 2021 Jul;
27:596522.
PMID: 34257546
Abrogation of Notch signaling, which is pivotal for lung development and pulmonary epithelial cell fate decisions was shown to be involved in the aggressiveness and the differentiation of lung carcinomas....
13.
Jori B, Schatz S, Kaller L, Kah B, Roeper J, Ramdani H, et al.
Cancers (Basel)
. 2021 Jul;
13(12).
PMID: 34201252
Since 2009, several first, second, and third generation tyrosine kinase inhibitors (TKI) have been approved for targeted treatment of mutated metastatic non-small lung cancer (NSCLC). A vast majority of patients...
14.
Griesinger F, Eberhardt W, Nusch A, Reiser M, Zahn M, Maintz C, et al.
Lung Cancer
. 2021 May;
157:167.
PMID: 34049721
No abstract available.
15.
Tosetti B, Ward B, Grumme D, Herb M, Schramm M, Utermohlen O, et al.
Front Immunol
. 2021 Apr;
12:633629.
PMID: 33868252
Although the crucial role of professional phagocytes for the clearance of infections is well-established, several studies indicate an adverse role of leukocytes in the dissemination of during infection. Since only...
16.
Iyer A, Radonic T, Heukamp L, Thunnissen E, Daniels J
ERJ Open Res
. 2021 Mar;
7(1).
PMID: 33778057
Inflammatory myofibroblastic tumours (IMT) are a rare cause of endobronchial masses in adults. Surgery has been the mainstay of treatment of endobronchial IMTs, based on the potential for recurrence. Interventional...
17.
Sebastian M, Eberhardt W, Hoffknecht P, Metzenmacher M, Wehler T, Kokowski K, et al.
Lung Cancer
. 2021 Feb;
154:51-61.
PMID: 33611226
Objectives: After decades of unsuccessful efforts in inhibiting KRAS, promising clinical data targeting the mutation subtype G12C emerge. Since little is known about outcome with standard treatment of patients with...
18.
Griesinger F, Eberhardt W, Nusch A, Reiser M, Zahn M, Maintz C, et al.
Lung Cancer
. 2020 Dec;
152:174-184.
PMID: 33358484
Objectives: An increasing number of treatment-determining biomarkers has been identified in non-small cell lung cancer (NSCLC) and molecular testing is recommended to enable optimal individualized treatment. However, data on implementation...
19.
Stenzinger A, van Tilburg C, Tabatabai G, Langer F, Graf N, Griesinger F, et al.
Pathologe
. 2020 Dec;
42(1):103-115.
PMID: 33258061
NTRK gene fusions are sporadic genetic alterations that can occur across tumor entities. Whereas they are quite rare in most solid tumors they are present at much higher frequencies in...
20.
Majewska H, Gorczynski A, Czapiewski P, Menon R, Mueller J, Lakis S, et al.
Virchows Arch
. 2020 Nov;
478(5):933-941.
PMID: 33237469
Salivary gland carcinomas represent a heterogeneous group of poorly characterized head and neck tumors. The purpose of this study was to evaluate ALK gene and protein aberrations in a large,...