Luise Rupp
Overview
Explore the profile of Luise Rupp including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
31
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Recent Articles
1.
Crespo E, Loureiro L, Stammberger A, Hoffmann L, Berndt N, Hoffmann A, et al.
NPJ Precis Oncol
. 2025 Feb;
9(1):42.
PMID: 39924591
Applying CAR T-cell therapy to treat solid tumors is especially challenging due to the immunosuppressive tumor microenvironment (TME). While our modular RevCAR system enhances the safety and controllability of CAR...
2.
Priego N, de Pablos-Aragoneses A, Perea-Garcia M, Pieri V, Hernandez-Oliver C, Alvaro-Espinosa L, et al.
Cancer Discov
. 2024 Oct;
15(1):179-201.
PMID: 39354883
Immunotherapies against brain metastases have shown clinical benefits when applied to asymptomatic patients, but they are largely ineffective in symptomatic cases for unknown reasons. Here, we dissect the heterogeneity in...
3.
Kirchner J, Plesca I, Rothe R, Resag A, Lock S, Benesova I, et al.
Front Immunol
. 2024 Jun;
15:1414298.
PMID: 38938577
Head and neck squamous cell carcinoma (HNSCC) is one of the most common tumor entities worldwide, with human papillomavirus (HPV) infection contributing to cancer development. Conventional therapies achieve only limited...
4.
Rupp L, Dietsche I, Kiessler M, Sommer U, Muckenhuber A, Steiger K, et al.
Front Immunol
. 2024 Apr;
15:1378190.
PMID: 38629072
Pancreatic ductal adenocarcinoma (PDAC) is typically diagnosed at advanced stages and associated with early distant metastasis and poor survival. Besides clinical factors, the tumor microenvironment (TME) emerged as a crucial...
5.
Ibneeva L, Singh S, Sinha A, Eski S, Wehner R, Rupp L, et al.
PLoS Biol
. 2024 Feb;
22(2):e3002517.
PMID: 38422172
A subpopulation of deeply quiescent, so-called dormant hematopoietic stem cells (dHSCs) resides at the top of the hematopoietic hierarchy and serves as a reserve pool for HSCs. The state of...
6.
Loureiro L, Hoffmann L, Neuber C, Rupp L, Arndt C, Kegler A, et al.
J Exp Clin Cancer Res
. 2023 Dec;
42(1):341.
PMID: 38102692
Background: Chimeric antigen receptor (CAR) T-cells are a promising approach in cancer immunotherapy, particularly for treating hematologic malignancies. Yet, their effectiveness is limited when tackling solid tumors, where immune cell...
7.
Rupp L, Resag A, Potkrajcic V, Warm V, Wehner R, Johrens K, et al.
Front Immunol
. 2023 Jun;
14:1185197.
PMID: 37261361
Soft tissue sarcomas (STS) form a heterogeneous group of tumors sharing a mesenchymal origin. Despite good local control of the disease, the occurrence of distant metastases often limits survival of...
8.
Digomann D, Strack J, Heiduk M, Plesca I, Rupp L, Reiche C, et al.
Cancers (Basel)
. 2023 May;
15(8).
PMID: 37190254
Immunotherapy has shown promising results in multiple solid tumors and hematological malignancies. However, pancreatic ductal adenocarcinoma (PDAC) has been largely refractory to current clinical immunotherapies. The V-domain Ig suppressor of...
9.
Bayerl F, Bejarano D, Bertacchi G, Doffin A, Gobbini E, Hubert M, et al.
Eur J Immunol
. 2023 Jan;
53(11):e2249923.
PMID: 36623939
This article is part of the Dendritic Cell Guidelines article series, which provides a collection of state-of-the-art protocols for the preparation, phenotype analysis by flow cytometry, generation, fluorescence microscopy, and...
10.
Schumann T, Costas Ramon S, Schubert N, Mayo M, Hega M, Maser K, et al.
J Exp Med
. 2022 Nov;
220(1).
PMID: 36346347
Defects in nucleic acid metabolizing enzymes can lead to spontaneous but selective activation of either cGAS/STING or RIG-like receptor (RLR) signaling, causing type I interferon-driven inflammatory diseases. In these pathophysiological...